Results 81 to 90 of about 69,242 (204)

Current advances in 2025: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee

Transfusion, EarlyView.
Nabiha H. Saifee, Jennifer Andrews, Mary Berg, Stella T. Chou, Mischa Covington, Elizabeth P. Crowe, Ruchika Goel, Juliana A. Guarente, Tina Ipe, Jeremy W. Jacobs, Jessica Jacobson, Cyril Jacquot, Jenna Khan, Thane A. Kubik, Theodros Mamo, Michael F. Murphy, Kerry O'Brien, Monica B. Pagano, Anil K. Panigrahi, Jacqueline N. Poston, Scott E. Potter, Simon J. Stanworth, Moritz Stolla, Alyssa Ziman, Ryan A. Metcalf   +24 more
wiley   +1 more source

What Are Appropriate Initial and Salvage Therapies for Patients with Thrombotic Thrombocyopenic Purpura (TTP)?

Acta Medica, 2004
Although much has been learned about the pathophysiologic process of thrombotic thrombocytopenic purpura (TTP), both diagnostically and therapeutically, since its initial description by Moschowitz in 1924, its etiology and treatments remain, in many ...
Leo McCarthy, Atillio Orazi, Charles Miraglia, Daniel Waxman, Elaine Skipworth, Constance Danielson   +5 more
doaj   +1 more source

Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia. [PDF]

, 2009
The activity of ADAMTS13, the von Willebrand factor (VWF) cleaving protease is low in several conditions, including HELLP (haemolysis, elevated liver enzymes, and low platelet count) syndrome.
Hársfalvi, Jolán, Molvarec, Attila, Gombos, Tímea, Udvardy, Miklós László, Cervenak, László, Derzsy, Zoltán, Prohászka, Zoltán, Rigó, János, Bõze, Tamás, Makó, Veronika   +9 more
core   +1 more source

Pathophysiology of thrombotic thrombocytopenic purpura [PDF]

Blood, 2017
AbstractThe discovery of a disintegrin-like and metalloproteinase with thrombospondin type 1 motif, member 13 (ADAMTS13) revolutionized our approach to thrombotic thrombocytopenic purpura (TTP). Inherited or acquired ADAMTS13 deficiency allows the unrestrained growth of microthrombi that are composed of von Willebrand factor and platelets, which ...
openaire   +2 more sources

Thrombotic Thrombocytopenic Purpura: Three Peripartum Cases and Diagnostic Challenges

, 2013
Thrombotic thrombocytopenic purpura (TTP) is a medical emergency characterized by occlusive microangiopathy due to intravascular platelet aggregation. This event results in damage to the red blood cells (RBCs) known as microangiopathic hemolytic anemia ...
Mohd Nazri Hassan, Azlan Husin, Suhair Abbas Ahmed, Rapiaah Mustaffa, Wan Zaidah Abdullah, Wan Suriana Wan Ab Rahman   +5 more
core   +1 more source

Pembrolizumab-induced thrombotic thrombocytopenic purpura

, 2019
Introduction Pembrolizumab is a humanised monoclonal antibody targeting the receptor programmed cell death protein-1 (PD-1), with anti-tumour activity demonstrated for many malignancies.
Collins, Joel T., Dickey, Marcus S.R., Wisniowski, Brendan L., Raina, Anant J., Nguyen, Andrew D.K., Karki, Bhaskar, Gilbar, Peter J.   +6 more
core   +1 more source

Thrombotic Thrombocytopenic Purpura Associated with Clopidogrel [PDF]

, 2000
BACKGROUND: The antiplatelet drug clopidogrel is a new thienopyridine derivative whose mechanism of action and chemical structure are similar to those of ticlopidine.
Bell, William, McCarthy, Leo, Davidson, Charles, Tarantolo, Stefano, Sarode, Ravindra, Tsai, Han-Mou, Moake, Joel, Carwile, John, Feldman, Marc, Bennett, Charles, Hatfield, Amy, Connors, Jean   +11 more
core   +1 more source

Opana® ER induced thrombotic thrombocytopenic purpura

, 2015
Nabil Kotbi, Bernadine Han, Duncan Cheng, Anna E Odom Department of Psychiatry, Weill Cornell Medical College, New York-Presbyterian Hospital, White Plains, NY, USA Abstract: We present the case of a patient who developed thrombotic thrombocytopenic ...
Cheng D, Han B, Kotbi N, Odom AE
core  

Thrombotic thrombocytopenic purpura mimicking an acute meningoencephalitis

, 2011
Thrombotic thrombocytopenic purpura is a rare, life-threatening disease characterized by thrombocytopenia, microangiopathic haemolytic anaemia and organ dysfunction, e.g. neurological impairment and renal insufficiency.
Felicani C, Grasso V, Tovoli F, Serra M, Fabbri A, Caio G, DE GIORGIO, Roberto, Volta U., Barbara G   +8 more
core   +2 more sources

Management of thrombotic thrombocytopenic purpura: current perspectives

, 2014
Piers Blombery, Marie Scully Department of Haematology, University College London Hospital, London, UK Abstract: Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening thrombotic microangiopathy which causes significant morbidity and ...
Blombery P, Scully M
core