Results 91 to 100 of about 179,287 (301)
, 2014 Few cases of a left atrial thrombus without mitral valve disease have been reported. We present an unusual case in which a patient presented to the emergency department with syncope and acute cerebral ischemia caused by a ball thrombus originating from ...
J. Lee Garvey +6 more
core +1 more source
Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity
Advanced Science, EarlyView.This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj +25 more
wiley +1 more source
, 2012 Mechanical thrombectomy is increasingly applied during the treatment of acute stroke. Various devices have been advocated with different sites of force effect at the thrombus.
Brekenfeld, Caspar +7 more
core +1 more source
Thermochemical Micro‐Explosion for Prompt Thrombolysis via Proximal Injection of Liquid Alkali Metal
Advanced Science, EarlyView.We report a micro‐explosive thermochemical thrombolysis (METCT) therapy via injectable liquid alkali metal encapsulated in dimethyl silicone (LAM@oil). METCT enables prompt and safe vascular recanalization within 90 s. Critically, the LAM@oil system demonstrates significantly higher thrombolytic efficacy compared to clinically available thrombolytic ...
Xin Liao +7 more
wiley +1 more source
Advanced Science, EarlyView.Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin +8 more
wiley +1 more source
Thrombus Aspiration in Patients With High Thrombus Burden in the TOTAL Trial
, 2018 BackgroundRoutine thrombus aspiration in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) does not improve clinical outcomes.
Tsang, Michael +18 more
core +1 more source
Advanced Science, EarlyView.Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta +10 more
wiley +1 more source
A Smart Fluid‐Hydraulic System Based on MRF Valve Control and Its Application in Flexible Grasping
Advanced Science, EarlyView.This study introduces a smart fluid hydraulic system using MRF valve control for flexible gripping. An MRF‐MSV with an integrated excitation coil and micro‐textured damping channels is designed and validated; micro‐texturing increases hydraulic resistance. Coupled with a soft actuator, the MRF‐MSV enables dynamic bending and grasping.
Linfeng Huo +5 more
wiley +1 more source
, 2012 We present the case of right ventricular thrombus formation associated with a right ventricular infarct secondary to a proximal right coronary artery thrombus, which was not evident on transthoracic echocardiography but detected on both delayed ...
Tsang, Benjamin K-T +10 more
core +1 more source
Advanced Science, EarlyView.CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen +19 more
wiley +1 more source