Results 71 to 80 of about 184,454 (263)

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Supraceliac Aortic Mural Thrombus Presenting with Peripheral or Mesenteric Acute Ischemia: A Scoping Review and Case Series

Indian Journal of Vascular and Endovascular Surgery
Primary aortic mural thrombus (PAMT) leads to visceral and lower limb embolism in patients. The etiology of PAMT is usually idiopathic. Supra-celiac aortic mural thrombus (SCAT) has been thought to have a different etiological basis compared to PAMT ...
Bricilla Gnana Preethe, Jithin Jagan Sebastian, Sairam Subramanian   +2 more
doaj   +1 more source

“Atherosclerotic” thrombus.

, 2016
CD3+ cells (brown) corresponding to T cells in an “atherosclerotic” thrombus.
Carlos Riquelme Bareiro (2735182), Kyriakos Lobotesis (2735173), Grégory Gascou (2735161), Omer Eker (2735179), Valérie Rigau (424911), Paolo Machi (2735170), Valérie Costes (652651), Alain Bonafé (283383), Nicolas Molinari (75348), Xavier Ayrignac (2735185), Cyril Dargazanli (2735158), Astrid Corlobé (2735155), Isabelle Mourand (2735176), Vincent Costalat (2735164), Caroline Arquizan (2735167)   +14 more
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Computational Fluid Dynamics of Blood Flow in an Extracorporeal Blood Circuit for the Analysis of Thrombogenic Hemodynamic Factors

Journal of Biomechanical Science and Engineering, 2011
Blood flow in a filter for an extracorporeal blood circuit was analyzed numerically to assess fluid mechanical quantities related to thrombogenesis. Results showed stagnant flow regions, in particular at the downstream side of the ceiling of a filter.
Masanori NAKAMURA, Haruka TAKIMOTO, Shigeo WADA   +2 more
doaj   +1 more source

“Cardioembolic” thrombus.

, 2016
CD3+ cells (brown) corresponding to T cells in a “cardioembolic” thrombus.
Carlos Riquelme Bareiro (2735182), Kyriakos Lobotesis (2735173), Grégory Gascou (2735161), Omer Eker (2735179), Valérie Rigau (424911), Paolo Machi (2735170), Valérie Costes (652651), Alain Bonafé (283383), Nicolas Molinari (75348), Xavier Ayrignac (2735185), Cyril Dargazanli (2735158), Astrid Corlobé (2735155), Isabelle Mourand (2735176), Vincent Costalat (2735164), Caroline Arquizan (2735167)   +14 more
core   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

Advanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong, Xingjin Li, Tao Hu, Qianqian Lu, Xiaoxu Zhang, Xi Chen, Yifan Luo, Zhong Zuo, Ronald Man Yeung Wong, Miao Xu, Tiancong Zhao, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Left Ventricular Thrombus in Cardiomyopathy : Echocardiographic Assessment [PDF]

, 1994
24-year-old female presented congestive heart failure caused by dilated cardiomyopathy and two patterns of the left ventricular thrombus. Protruding thrombus, formed on the 8 th day of hospitalization, was successufully dissolved by the intravenous ...
Mori, H., Yano, K.., Yamanaka, H., Haga, Y., Izumikawa, K.., Kose, N., Hara, K.., Shimizu, A..   +7 more
core   +2 more sources

Schematic representation of the proposed thrombus model.

, 2023
Schematic representation of the proposed thrombus model.
Enrico Napoli (14573246), Alessandra Monteleone (10200194), Alessia Viola (13042044), Gaetano Burriesci (10200203)   +3 more
core   +1 more source