Results 101 to 110 of about 323,234 (402)
Cobimetinib and trametinib inhibit platelet MEK but do not cause platelet dysfunction [PDF]
, 2018 The MEK inhibitors cobimetinib and trametinib are used in combination with BRAF inhibitors to treat metastatic melanoma but increase rates of hemorrhage relative to BRAF inhibitors alone.
Bye, Alex P. +6 more
core +4 more sources
Stroke, 2019 Background and Purpose— Mechanical thrombectomy may involve multiple attempts to retrieve the occluding thrombus. This study examined the composition of thrombus fragments retrieved with each pass of a device during the thrombectomy procedure.
S. Duffy +11 more
semanticscholar +1 more source
Arteriosclerosis, Thrombosis and Vascular Biology, 2020 Supplemental Digital Content is available in the text. Objective: Atherothrombosis occurs upon rupture of an atherosclerotic plaque and leads to the formation of a mural thrombus.
Muhammad Usman Ahmed +17 more
semanticscholar +1 more source
Advanced Healthcare Materials, EarlyView.This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren +13 more
wiley +1 more source
Myocardial ischemia after orthotopic liver transplantation [PDF]
, 1994 A hypercoagulable state exists after orthotopic liver transplantation. This hematologic abnormality may predispose patients to coronary thrombosis and unstable angina.
Ambrose +24 more
core +1 more source
Current Challenges in Hemostasis and Advances in Particle‐Assisted Styptic Devices
Advanced Healthcare Materials, EarlyView.Here persistent limitations in hemostatic technologies are highlighted and cutting‐edge biomimetic, microparticle‐assisted, and nanoengineered systems with integrated drug delivery are showcased. Moreover, the article identifies fresh directions toward the next‐generation of multifunctional hemostatic devices with superior efficacy and accessibility ...
Daniele Baiocco +4 more
wiley +1 more source
Early recurrent ischemic stroke complicating intravenous thrombolysis for stroke: incidence and association with atrial fibrillation [PDF]
, 2010 <p><b>Background and Purpose:</b> Mechanisms of early neurologic deterioration after treatment with intravenous, recombinant, tissue-type plasminogen activator (IV rt-PA) include symptomatic intracerebral hemorrhage (SICH) and early ...
Awadh, M. +5 more
core +1 more source
Advanced Healthcare Materials, EarlyView.A robust heparin‐mimicking coating based on sulfated polyglycerol is constructed via layer‐by‐layer assembly on bloodcontacting surfaces. The coating exhibits long‐term anticoagulant and anti‐inflammatory properties by resisting protein adsorption, preventing platelet activation, and suppressing immune responses, offering a promising strategy for ...
Kunpeng Liu +3 more
wiley +1 more source
Use of Computed Tomography Scan to Rule Out Phantom Thrombus in the Left Atrial Appendage
Journal of Cardiac Arrhythmias, 2020 Objective: The aim of study was to evaluate the utility of CT scan with delayed acquisition protocol to exclude LAA thrombus. The occurrence of left atrial appendage (LAA) thrombus is a frequent complication of atrial fibrillation (AF) and increases the ...
Luis Arabia +6 more
doaj +1 more source
Portal Venous Thrombosis Associated with Use of Etonogestrel/ethinyl Estradiol Vaginal Ring [PDF]
, 2020 Introduction: Portal venous thrombosis is a life-threatening cause of abdominal pain. In younger patients, heritable thrombophilias, pregnancy, tobacco use, and oral contraceptives are associated.Case Report: A 26-year-old woman prescribed contraceptive ...
Bailey, Katelynn E. +1 more
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