Results 241 to 250 of about 167,463 (313)

Ischaemic stroke and 5‐fluorouracil or capecitabine: A systematic review and meta‐analysis of harms and a retrospective study of the WHO pharmacovigilance database

British Journal of Pharmacology, EarlyView.
Abstract Aim Fluoropyrimidines, including 5‐fluorouracil (5‐FU) and capecitabine, are cornerstone antineoplastic agents for cancer. Case reports suggest that these drugs may be associated with an under‐recognised risk of ischaemic stroke or transient ischaemic attack (TIA).
Sophie Nguyen, Ines Bentahrour, Camille Guerin, Charles Dolladille, Angélique Da Silva, François Cherifi, Elise‐Marie Minoc, Pierre‐Marie Morice, Nicolas Jacquin, Christophe Le Tourneau, Joachim Alexandre, Ahmad Nehme, Etienne Bastien   +12 more
wiley   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Splenic Vein Tumor Thrombosis in a Patient With an Oligometastatic Pancreatic Neuroendocrine Tumor: A Case Report and Literature Review. [PDF]

Cureus
Francis A, Cox T, Khader A, Khan A, Hatfield BS, Bello R.   +5 more
europepmc   +1 more source

A Multicellular Coordinated Network Driving Lymphovascular Space Invasion in Endometrioid Endometrial Carcinoma

Cell Proliferation, EarlyView.
Single‐cell and spatial profiling reveal that lymphovascular space invasion in endometrioid endometrial carcinoma is driven by coordinated interactions among metastatic epithelium, fibroblasts, immune cells, and endothelium. This multicellular network promotes matrix remodelling, angiogenesis, and immune evasion, forming a pro‐metastatic niche that ...
Wendi Guo, Tianxiang Liu, Runling Ren, Na Li, Wenwen Zhang, Jingwen Si, Yongjun Piao, Yuanjing Hu   +7 more
wiley   +1 more source

Glue Embolus-Induced Portosplenic Thrombosis in Transjugular Intrahepatic Portosystemic Shunt: A Novel Finding During Liver Transplantation. [PDF]

Am J Case Rep
Kotadia MS, Saulino D, Soma D, Bashir AH.   +3 more
europepmc   +1 more source

Intracardiac thrombus formations despite continuous oral anticoagulation in atrial fibrillation patients undergoing catheter ablation procedures: pilot development of a machine learning prediction model. [PDF]

Front Cardiovasc Med
Ratajczak F, Hohendanner F, Haack S, Boldt L, Parwani AS, Blaschke F, Schneider-Reigbert M, Spinka F, Bock M, Meyer A, Heil E, Hindricks G, Schoeppenthau D.   +12 more
europepmc   +1 more source

Histopathological Analysis of Thrombi in Acute Ischemic Stroke: An Exploratory Study of Thrombus Composition and CD34-Positive Endothelial Cells. [PDF]

Diagnostics (Basel)
Aksoy S, Vural A, Kulaç İ, Selçuk HH, Kızılırmak AB, Özdemir YG, Yılmaz B.   +6 more
europepmc   +1 more source

Cholestatic Hepatitis in Young Migrants Exposed to Fuel Vapours: An Emerging Toxicity From the Mediterranean Sea

Acta Paediatrica, EarlyView.
Antonio Corsello, Simone Maria Calogero Gramaglia, Giuseppe Gramaglia, Gerlando Verruso, Giusy Ranucci   +4 more
wiley   +1 more source

Real-time transesophageal echocardiography-guided surgical resection of hepatocellular carcinoma with inferior vena cava tumor thrombus: a case report. [PDF]

AME Case Rep
Bian L, Liu T, Zhang Z, Zhang J, Shao Y.
europepmc   +1 more source

Proteomic Profiling Captures Residual Cardiovascular Risk Beyond the PREVENT Model in Individuals With Cardiovascular–Kidney–Metabolic Syndrome Stages 2–3

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background Cardiovascular–kidney–metabolic (CKM) syndrome reflects complex pathobiological interactions among metabolic disorders, kidney injury, and cardiovascular disease (CVD). Stages 2 and 3 represent critical phases of disease progression characterised by high pathological heterogeneity.
Xuefei Han, Jiacheng Ding, Jingqian Li, Yiyin Gao, Yunqian Li   +4 more
wiley   +1 more source