Results 101 to 110 of about 33,782 (335)

Small Opening Flow Linearity Optimization of High-Pressure and Large-Flow Two-Way Proportional Throttle Valve

open access: yesMachines
As a key component of the die-casting machine, the flow linearity of the high-pressure, large-flow proportional throttle valve is a critical factor affecting injection accuracy at low openings.
Baosheng Wang   +5 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Design and performance analysis of small hole throttling aerostatic bearings

open access: yesJixie qiangdu
Focusing on the performance of single-throttle-orifice aerostatic bearings, this study investigates the effects of design parameters on load capacity and stiffness, aiming to optimize the structural design and performance of aerostatic bearings.
QIU Dezhong, LEI Weining, XUE Yaping
doaj  

Review on Joule-Thompson Effect Throttle Cryocooler

open access: yesZhileng xuebao, 2019
The recent development of micro-sized Joule–Thomson (J-T) effect throttle cryocoolers is reviewed in this paper. The existing technology and research results are summarized from the theoretical research and structural evolution of the cryocooler.
She Hailong   +3 more
doaj  

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

open access: yesFEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi   +5 more
wiley   +1 more source

Simulation and Optimization of Throttle Flowmeter with Inner-Outer Tube Element

open access: yesMeasurement Science Review, 2017
In order to solve the dilemma between the smaller pressure loss and the larger flow measurement signal in traditional throttle flowmeters, a throttle structure with the inner-outer tube was designed and analyzed.
Meng Jiang   +3 more
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Development and Testing of a Fast-Acting, 8-Bit, Digital Throttle for Hybrid Rocket Motors

open access: yesFire
The potential for throttle control of hybrid rocket systems has long been known as a potential advantage for a variety of applications. Because only a single flow path is controlled, theoretically, hybrids should be significantly easier to throttle than ...
Stephen A. Whitmore
doaj   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

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