Results 151 to 160 of about 34,123 (307)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Research into performance optimization control strategy of a hydrostatic drive bulldozer based on the constant speed cruise. [PDF]

Sci Rep
Qiang H, Li H, Kang S, Liu K, Yang J, Luo X.   +5 more
europepmc   +1 more source

Reflexive BFT: Mitigating Granular Safety Risks via Variance-Based Throttling

Matthew Parsons
openalex   +1 more source

On the Characteristics of Hydraulic Copying Control Device using Throttle Valve (1st Report)

, 1973
Shinobu KATO, Katsumi YAMAGUCHI, Etsuo Marui   +2 more
openalex   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Flood Algorithm-Tuned PID-F Controller with a Modified Objective Function for Robust and Noise-resilient Speed Control of Nonlinear SparkIgnition Engines. [PDF]

Sci Rep
Ekinci S, Izci D, Turkeri C, Bajaj M, Rubanenko O.   +4 more
europepmc   +1 more source

Comparative effectiveness of throttled and relay rocket engines for low-gravity near-Earth flights

, 2019
Iulian Vasiliev, Ya. V. Tkachenko
openalex   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Enhanced CNN based approach for IoT edge enabled smart car driving system for improving real time control and navigation. [PDF]

Sci Rep
Sudhakar M, Vivekrabinson K.
europepmc   +1 more source