Results 151 to 160 of about 94,849 (390)

Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment

open access: yesFEBS Letters, EarlyView.
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke   +2 more
wiley   +1 more source

Development and Testing of a Fast-Acting, 8-Bit, Digital Throttle for Hybrid Rocket Motors

open access: yesFire
The potential for throttle control of hybrid rocket systems has long been known as a potential advantage for a variety of applications. Because only a single flow path is controlled, theoretically, hybrids should be significantly easier to throttle than ...
Stephen A. Whitmore
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Lunar landing flight research vehicle Patent [PDF]

open access: yes, 1965
Lunar landing flight research ...
Allen, J. G., Jr., Levin, K. L.
core   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

The implementation and operation of a variable-response electronic throttle control system for a TF-104G aircraft [PDF]

open access: yes
During some flight programs, researchers have encountered problems in the throttle response characteristics of high-performance aircraft. To study and to help solve these problems, the National Aeronautics and Space Administration Ames Research Center's ...
Neal, Bradford, Sengupta, Upal
core   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Time and Energy Managed Operations (TEMO): Cessna Citation II Flight Trials [PDF]

open access: yes, 2016
From 9-26 October 2015 the Netherlands Aerospace Centre (NLR) in cooperation with Delft University of Technology (DUT) has executed Clean Sky flight trials with the Cessna Citation II research aircraft.
Bussink, Frank   +3 more
core  

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