Results 81 to 90 of about 33,782 (335)

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

open access: yesFEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg   +2 more
wiley   +1 more source

Prediction of the Maximum Erosion Rate of Gas–Solid Two-Phase Flow Pipelines

open access: yesEnergies, 2018
Erosion is one of the important reasons for the thickness decrease and perforation of the pipe walls. Understanding the gas–solid two-phase flow pipe erosion mechanism is the basis for monitoring pipe erosion.
Jingyuan Xu   +3 more
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Visualization of flow phenomena in hydraulic throttle valves of plastics

open access: yes, 2018
Using elements made of plastics in hydraulic drives and controls encounters problems, for example related to strength. However, the advantage of solutions with plastics manifests itself, among others in possibility of shaping hydraulic elements in ...
Michael D. Banas   +3 more
semanticscholar   +1 more source

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

open access: yesFEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Automotive compressor: effect of an electric throttle in the upstream circuit on the surge limit

open access: yesMATEC Web of Conferences, 2018
On vehicles equipped with a turbocharged engine, there is a risk of compressor surge. This surge generates instabilities that lead to driving inconvenience, or even mechanical failure of the supercharging system.
Podevin Pierre   +5 more
doaj   +1 more source

CALCULATION OF THE HYDRAULIC BOOM LIFTING MECHANISM WHILE LOWERING PROCESS

open access: yesВестник СибАДИ, 2019
Introduction. The paper considers the throttle regulation providing flow continuity of working fluid for the purpose of cavitations’ prevention. The throttle regulation in a hydraulic actuator of the load-lifting mechanism under the influence of static ...
G. Yu. Zubrilov   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy