Results 181 to 190 of about 15,081,754 (391)
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Shaping the flow characteristics of a proportional directional valve. [PDF]
Sci RepKosek M, Sliwinski P.
europepmc +1 more source
Control concepts for the alleviation of windshears and gusts [PDF]
Automatic control system design methods for gust and shear alleviation were studied. It is shown that automatic gust/shear alleviation systems can be quite effective if both throttle and elevator are used in harmony to produce the forces and moments ...
Govindaraj, K. S., Rynaski, E. G.
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
The racer's gaze: Visual strategy in high-speed sports expertise. [PDF]
J VisLappi O +5 more
europepmc +1 more source
Control of electronic throttle valve using model predictive control
, 2016 Anshul Khinchi, M. P. R. Prasad
openalex +1 more source
A preliminary investigation of the use of throttles for emergency flight control [PDF]
A preliminary investigation was conducted regarding the use of throttles for emergency flight control of a multiengine aircraft. Several airplanes including a light twin-engine piston-powered airplane, jet transports, and a high performance fighter were ...
Burcham, F. W., Jr. +4 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
High-Fidelity Interactive Motorcycle Driving Simulator with Motion Platform Equipped with Tension Sensors. [PDF]
Sensors (Basel)Svoboda J +4 more
europepmc +1 more source