Results 41 to 50 of about 3,380 (291)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Mathematical Modeling and Validation on a New Valve Core of the Throttle Valve in MPD
Advances in Mechanical Engineering, 2013 To achieve different demands for pressure control in managed pressure drilling (MPD), the relationship between the pressure difference and the valve opening was analyzed in the working process of MPD throttle. The throttle flow area equation and the flow
Y. K. Fu +3 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Development and Testing of a Fast-Acting, 8-Bit, Digital Throttle for Hybrid Rocket Motors
FireThe potential for throttle control of hybrid rocket systems has long been known as a potential advantage for a variety of applications. Because only a single flow path is controlled, theoretically, hybrids should be significantly easier to throttle than ...
Stephen A. Whitmore
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Synchronization in multi-motor hydromechanical systems
Advanced Engineering Research, 2022 Introduction. The paper submits the analysis of existing design solutions of flow dividers used to synchronize hydraulic drives of working bodies of technological and mobile machines.
A. T. Rybak +3 more
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Engineering Applications of Computational Fluid Mechanics, 2019 The purpose of this paper is to study the surge control effects of centrifugal compressors with active magnetic bearings (AMBs) under several operating conditions.
Xudong Guan +4 more
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source