Results 51 to 60 of about 3,380 (291)

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Fault Tolerant Control of Electronic Throttles with Friction Changes [PDF]

open access: yesElectronics, 2019
To enhance the reliability of the electronic throttle and consequently the vehicles driven by the internal combustion engines, a fault tolerant control strategy is developed in this paper. The proposed method employs a full-order terminal sliding mode control in conjunction with an adaptive radial basis function network to estimate change rate of the ...
Haiying Qi   +6 more
openaire   +3 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Comparison of the Accelerator-Pedal-to-Engine-Control-Module Interfaces on Vehicles With Low and High Reported Rates of Unintended Acceleration

open access: yesIEEE Access, 2015
This paper examines the AP-to-ECM interfaces of five vehicles equipped with electronic throttle control systems. All five vehicles employ simple voltage level sensing from two or three sensors in the accelerator pedal assembly.
Dexin Zhang, Todd H. Hubing
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

A Throttle and Brake Fuzzy Controller: Towards the Automatic Car

open access: yes, 2003
Trabajo presentado en la International Conference on Computer Aided Systems Theory (EUROCAST 2003), celebrada en Las Palmas de Gran Canaria (España), del 24 al 28 de febrero de 2003 It is known that the techniques under the topic of Soft Computing have a strong capability of learning and cognition, as well as a good tolerance to uncertainty and ...
Naranjo, José E.   +4 more
openaire   +3 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Car-following Model of Connected Cruise Control Vehicles to Mitigate Traffic Oscillations

open access: yesPromet (Zagreb), 2019
With the aim of mitigating traffic oscillations, this paper extends a car-following model for Connected Cruise Control (CCC) systems by considering electronic throttle angles of multiple cars ahead. The linear stability condition of the proposed model is
Yanyan Qin, Hao Wang, Quan Chen, Bin Ran
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

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