Results 51 to 60 of about 11,511 (294)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Joint Throughput Maximization and Fair Uplink Transmission Scheduling in CDMA Systems

EURASIP Journal on Wireless Communications and Networking, 2009
We study the fundamental problem of optimal transmission scheduling in a code-division multiple-access wireless system in order to maximize the uplink system throughput, while satisfying the users quality-of-service (QoS) requirements and maintaining ...
Symeon Papavassiliou, Chengzhou Li
doaj   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

On UAV Selection and Position-Based Throughput Maximization in Multi-UAV Relaying Networks

IEEE Access, 2020
Due to flexibility in deployment and high mobility, unmanned aerial vehicles (UAVs) can improve the performance of cellular networks. In this paper, we focus on the UAV-assisted cooperative communication network where multiple UAVs serve as relays ...
Sandeep Kumar Singh, Kamal Agrawal, Keshav Singh, Chih-Peng Li, Wan-Jen Huang   +4 more
doaj   +1 more source

UMTS Capacity and Throughput Maximization for Different Spreading Factors [PDF]

, 2006
This article discusses UMTS capacity and throughput maximization for different spreading ...
Akl, Robert G., Nguyen, Son
core  

A power Allocation Algorithm for Throughput Maximization in Mobile Networks

, 2005
This paper focuses on the competitively optimal power-control and signal-shaping for "ad-hoc" networks composed by Multiple-Antenna noncooperative transmit /receive terminals affected by spatially colored MultiAccess Interference (MAI).
Enzo Baccarelli, GARZIA F., Fabio Garzia, Mauro Biagi, PELIZZONI C, Nicola Cordeschi, Cristian Pelizzoni, BIAGI, MAURO, CORDESCHI, Nicola, BACCARELLI, Enzo   +9 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Throughput Maximization in Delay-Critical and Energy-Aware SW-UAV-WNs Using Q-Learning

IEEE Open Journal of the Communications Society
Unmanned aerial vehicles (UAVs) are getting significant attention from both researchers and the industry due to their wide range of applications. Remote sensing is one such application, in which UAVs are deployed to sense remote areas and transmit the ...
Sreenivasa Reddy Yeduri, Neha Sharma, Om Jee Pandey, Linga Reddy Cenkeramaddi   +3 more
doaj   +1 more source

Throughput maximization of optical LEO-ground links [PDF]

SPIE Proceedings, 2012
The long-term throughput of optical links between a circular-LEO satellite and a ground station is assessed for systems with fixed and variable data rates. For a fixed data rate, we evaluate the minimum elevation angle above which the link should be established in order to maximize the throughput.
Perlot, Nicolas, De Cola, Tomaso
openaire   +1 more source