Results 31 to 40 of about 104,201 (266)
Open Access Rheumatology: Research and Reviews, 2020 Ali A Al-Omari,1 Anas AR Altamimi,2 Esra’a ALQuran,3 Abed Allah Ahmad Saleh,1 Qusai Mustafa Alyafawee,1 Mohammad Ziad Audat,4 Khaldoon Bashaireh1 1Department of Special Surgery, Division of Orthopedics, Faculty of Medicine, Jordan University of ...
Al-Omari AA +6 more
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Bone & Joint Open, 2022 Aims Osteoarthritis (OA) affecting the thumb carpometacarpal joint (CMCJ) is a common painful condition. In this study, we aimed to explore clinicians’ approach to management with a particular focus on the role of specific interventions that will inform ...
Benjamin J. F. Dean +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
LifeRhizarthrosis is the most frequent form of osteoarthritis and is responsible for pain, disability and reduced functionality. The aim of the study is to investigate the clinical effects of shock wave treatment in patients suffering from arthritis of the ...
Ilaria Covelli +8 more
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Thumbnail strain during pressing and plucking of a string
Journal of Biomechanical Science and Engineering, 2015 Human fingernails play an important role in daily life and while playing instruments. We previously showed that the strain generated at the radial and ulnar parts of the nail was asymmetric when the thumb pad was pressed down on a flat surface.
Satoshi SHIMAWAKI +3 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Cooperative activities of forearm muscles under loading applied to thumb or each finger
Journal of Biomechanical Science and Engineering, 2018 Human thumb and fingers are usually subjected to an external loading during daily activity. The information of how muscles in the forearm cooperate with each other in order to response to the external loading is still unknown.
Shigeru TADANO +6 more
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
بهداشت و ایمنی کار, 2017 Introduction: Nowadays, Snap-fits have many applications in the automotive industry, especially in assembly lines. They are used instead of the mechanical joints such as bolts, the cabling joints, and the car interior lining joints.
Hamed Salmanzadeh, Zohreh Shakeri Kebria
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