Results 41 to 50 of about 107,131 (219)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Severe Type 1 Thumb Boutonniere Deformity with Interphalangeal Joint Dislocation in a Young Patient: A Case Report

Journal of Orthopaedic Case Reports
Introduction: Thumb boutonniere deformity, commonly associated with autoimmune arthropathies, presents as metacarpophalangeal (MCP) joint flexion and interphalangeal (IP) joint hyperextension.
Sarthak Aggarwal, Jeffrey G Stepan
doaj   +1 more source

Unilateral Vibratory Stimulation Inhibits Contralateral Spinal Anterior Horn Cells in Homonymous Muscles for the First 75 Seconds [PDF]

Annals of Rehabilitation Medicine
Objective To investigate muscle tone changes over time in contralateral homonymous muscles when unilateral muscles are stimulated, using F-wave measurements, we examined whether vibratory stimulation on the contralateral homonymous muscle of the affected
Kenta Kunoh, Takahiro Takenaka, Daisuke Kimura, Toshiaki Suzuki   +3 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Back to basics with distal thumb reconstruction. Easy management of the incomplete amputation

Journal of Investigative Surgery, 2021
Thumb reconstruction has always been challenging for hand surgeons. The disability can severely influence the working and social life of the patient, even if just the distal phalanx is affected.
L Losco, J Kaciulyte, G Delia, A Bolletta, Federico Lo Torto, G Di Taranto, D Ribuffo, E Cigna   +7 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Reconstrucción no biológica del ligamento colateral cubital de la articulación metacarpofalángica del pulgar: Un estudio retrospectivo de casos y controles

Revista Iberoamericana de Cirugía de la Mano
Objetivo El objetivo de este análisis retrospectivo fue cotejar los resultados posoperatorios de la reconstrucción ligamentosa no biológica (RLNB) para lesiones crónicas que involucran la articulación metacarpofalángica (AMCF) y el ligamento ...
Sergi Barrera-Ochoa, Julio Adrian Martínez-Garza, Rita Pereira-Cavaca, Jose Prieto-Mere, Gerardo Mendez-Sanchez, Francisco Soldado   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source