Results 61 to 70 of about 152,966 (304)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Evaluation of the influence of the clips geometry on the mechanical stresses generated on the thumb during assembly work

بهداشت و ایمنی کار, 2017
Introduction: Nowadays, Snap-fits have many applications in the automotive industry, especially in assembly lines. They are used instead of the mechanical joints such as bolts, the cabling joints, and the car interior lining joints.
Hamed Salmanzadeh, Zohreh Shakeri Kebria
doaj  

Cost–Benefit Analysis in the Surgical Management of Thumb Carpometacarpal Osteoarthritis: Dual-Mobility Total Joint Replacement Versus Trapeziectomy with Ligament Reconstruction and Suspension Arthroplasty

Surgeries
Background: Trapeziometacarpal (TM) osteoarthritis (OA) is a common condition, especially among postmenopausal women, often requiring surgical intervention when conservative treatment fails.
Leopoldo Arioli, Giulia Frittella, Fatma Abidi, Edoardo Venturini, Matteo Guzzini   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Thumb Nursery : 1916 price list

, 1916
191
Henry G. Gilbert Nursery and Seed Trade Catalog Collection., Rasmussen, R. J., Thumb Nursery.   +2 more
core   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Severe Type 1 Thumb Boutonniere Deformity with Interphalangeal Joint Dislocation in a Young Patient: A Case Report

Journal of Orthopaedic Case Reports
Introduction: Thumb boutonniere deformity, commonly associated with autoimmune arthropathies, presents as metacarpophalangeal (MCP) joint flexion and interphalangeal (IP) joint hyperextension.
Sarthak Aggarwal, Jeffrey G Stepan
doaj   +1 more source

Unilateral Vibratory Stimulation Inhibits Contralateral Spinal Anterior Horn Cells in Homonymous Muscles for the First 75 Seconds [PDF]

Annals of Rehabilitation Medicine
Objective To investigate muscle tone changes over time in contralateral homonymous muscles when unilateral muscles are stimulated, using F-wave measurements, we examined whether vibratory stimulation on the contralateral homonymous muscle of the affected
Kenta Kunoh, Takahiro Takenaka, Daisuke Kimura, Toshiaki Suzuki   +3 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Back to basics with distal thumb reconstruction. Easy management of the incomplete amputation

Journal of Investigative Surgery, 2021
Thumb reconstruction has always been challenging for hand surgeons. The disability can severely influence the working and social life of the patient, even if just the distal phalanx is affected.
L Losco, J Kaciulyte, G Delia, A Bolletta, Federico Lo Torto, G Di Taranto, D Ribuffo, E Cigna   +7 more
doaj   +1 more source