Results 71 to 80 of about 152,966 (304)

Neuro-Based Thumb-Tip Force and Joint Angle Modelling for Development of Prosthetic Thumb Control

, 2013
Human fingers have a specific role that contributes to different hand functions. Among these fingers, the thumb plays the most special function as an anchor to many hand activities.
Sidek, Shahrul Na'im, Nor Anija Jalaludin, Jalaludin, Nor Anija, Abu Ubaidah Shamsudin, Shahrul Na'im Sidek, Shamsudin, Abu Ubaidah   +5 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Reconstrucción no biológica del ligamento colateral cubital de la articulación metacarpofalángica del pulgar: Un estudio retrospectivo de casos y controles

Revista Iberoamericana de Cirugía de la Mano
Objetivo El objetivo de este análisis retrospectivo fue cotejar los resultados posoperatorios de la reconstrucción ligamentosa no biológica (RLNB) para lesiones crónicas que involucran la articulación metacarpofalángica (AMCF) y el ligamento ...
Sergi Barrera-Ochoa, Julio Adrian Martínez-Garza, Rita Pereira-Cavaca, Jose Prieto-Mere, Gerardo Mendez-Sanchez, Francisco Soldado   +5 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Secondary thumb reconstruction in a mutilated hand

, 2016
The thumb plays an integral role in hand function. Traumatic amputation results in significant morbidity. With loss of the thumb, up to a 40% reduction in hand function may result. Thumb replantation must be attempted when possible.
Graham, David, Sabapathy, S Raja, Bhardwaj, Praveen   +2 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Trapeziometacarpal Joint Arthroplasty of the Thumb without Osseous Tunnels and Carpal Tunnel Release via a Radial Approach; Technique, and Results

The Surgery Journal, 2019
Background Numerous surgeries have been described for osteoarthritis of the trapeziometacarpal (TMC) joint. We describe the senior author's experience with his technique of concurrent arthroplasty of the TMC joint, and carpal tunnel release (CTR) via a ...
Chung Ming Chan, Efraín Farías Cisneros, Tsu-Min Tsai   +2 more
doaj   +1 more source

The clinical and cost effectiveness of splints for thumb base osteoarthritis: a randomized controlled clinical trial. [PDF]

, 2020
OBJECTIVES: To investigate the clinical effectiveness, efficacy and cost effectiveness of splints (orthoses) in people with symptomatic basal thumb joint OA (BTOA).
Dziedzic
core   +1 more source