Results 31 to 40 of about 107,131 (219)

Extracorporeal Shock Wave Therapy (ESWT) vs. Exercise in Thumb Osteoarthritis (SWEX-TO): Prospective Clinical Trial at 6 Months

Life
Rhizarthrosis is the most frequent form of osteoarthritis and is responsible for pain, disability and reduced functionality. The aim of the study is to investigate the clinical effects of shock wave treatment in patients suffering from arthritis of the ...
Ilaria Covelli, Silvana De Giorgi, Antonio Di Lorenzo, Angelo Pavone, Fabrizio Salvato, Francesco Rifino, Biagio Moretti, Giuseppe Solarino, Angela Notarnicola   +8 more
doaj   +1 more source

Thumbnail strain during pressing and plucking of a string

Journal of Biomechanical Science and Engineering, 2015
Human fingernails play an important role in daily life and while playing instruments. We previously showed that the strain generated at the radial and ulnar parts of the nail was asymmetric when the thumb pad was pressed down on a flat surface.
Satoshi SHIMAWAKI, Atsushi NAKAYAMA, Masataka NAKABAYASHI, Naotaka SAKAI   +3 more
doaj   +1 more source

A qualitative study exploring clinicians’ views on clinical trials in thumb carpometacarpal joint osteoarthritis

Bone & Joint Open, 2022
Aims Osteoarthritis (OA) affecting the thumb carpometacarpal joint (CMCJ) is a common painful condition. In this study, we aimed to explore clinicians’ approach to management with a particular focus on the role of specific interventions that will inform ...
Benjamin J. F. Dean, Cynthia Srikesavan, Robin Horton, Francine Toye   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Cooperative activities of forearm muscles under loading applied to thumb or each finger

Journal of Biomechanical Science and Engineering, 2018
Human thumb and fingers are usually subjected to an external loading during daily activity. The information of how muscles in the forearm cooperate with each other in order to response to the external loading is still unknown.
Shigeru TADANO, Yuuki TONSHO, Saran KEERATIHATTAYAKORN, Satoshi YAMADA, Yasuhiro NAKAJIMA, Masahide HARADA, Norimasa IWASAKI   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Evaluation of the influence of the clips geometry on the mechanical stresses generated on the thumb during assembly work

بهداشت و ایمنی کار, 2017
Introduction: Nowadays, Snap-fits have many applications in the automotive industry, especially in assembly lines. They are used instead of the mechanical joints such as bolts, the cabling joints, and the car interior lining joints.
Hamed Salmanzadeh, Zohreh Shakeri Kebria
doaj  

Cost–Benefit Analysis in the Surgical Management of Thumb Carpometacarpal Osteoarthritis: Dual-Mobility Total Joint Replacement Versus Trapeziectomy with Ligament Reconstruction and Suspension Arthroplasty

Surgeries
Background: Trapeziometacarpal (TM) osteoarthritis (OA) is a common condition, especially among postmenopausal women, often requiring surgical intervention when conservative treatment fails.
Leopoldo Arioli, Giulia Frittella, Fatma Abidi, Edoardo Venturini, Matteo Guzzini   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source