ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib+16 more
wiley +1 more source
Background and objective Video-assisted thoracoscopic surgery (VATS) theoretically offers advantages over open thymectomy for clinically early-stage (Masaoka-Koga stage I and II) thymic malignancies. However, longterm outcomes have not been well studied.
Hao WANG+23 more
doaj +1 more source
Intravenous flurbiprofen for post-thymectomy pain relief in patients with myasthenia gravis
Background Post-thymectomy pain in myasthenia gravis (MG) patients can inhibit breathing and coughing. Inappropriate usage of analgesics may exacerbate respiratory inhibition and even cause myasthenic crisis.
Su Chunhua+6 more
doaj +1 more source
Robot-Assisted Thoracic Surgery Thymectomy
Robotic thymectomy has been adopted recently and has been shown to be safe and feasible in treating thymic tumors and myasthenia gravis. The surgical indications of robotic technology are expanding, with advantages including an excellent surgical view ...
Samina Park
doaj +1 more source
Robot‐Assisted Versus Open Surgery for the Resection of Large Thymomas: A Retrospective Cohort Study
ABSTRACT Background Robot‐assisted thoracic surgery (RATS) is increasingly becoming the preferred surgical method for the resection of thymomas. We initiated the current study to evaluate perioperative outcomes and early recurrence associated with the surgical approach.
Benedikt Niedermaier+7 more
wiley +1 more source
Myasthenia gravis patients with anti-MuSK antibodies [Miastenija gravis kod bolesnika s pozitivnim protutijelima na MuSK] [PDF]
In myasthenia gravis (MG) patients without detectable anti-acetylcholine receptor (anti-AChR) antibody, referred to as seronegative myasthenia gravis patients, there is a variable proportion of patients with antibodies against the muscle specific kinase (
Bilić, Ervina+5 more
core
Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice [PDF]
El copyright pertenece a The Rockefeller University PressUnder physiological conditions, the vast majority of T cells differentiate in the thymus, an organ that provides an optimal microenvironment for T cell maturation and shapes the T cell repertoire ...
Andreu-Sánchez, Jose L.+5 more
core +1 more source
Herein, we present a case report of a young adult male diagnosed with primary squamous cell carcinoma of the trachea who underwent postoperative concurrent chemoradiotherapy utilizing intensity‐modulated radiation therapy and achieved long‐term survival. Abstract Objective The incidence of primary tracheal neoplasm is extremely rare.
Xueling Chen, Xuejian Ning, Tao Si
wiley +1 more source
Myasthenia. Surgical treatment and its effectiveness
The article reviews the problems of diagnostics and. treatment of myasthenia. The authors consider that thymectomy in modern conditions is founded, expedient and. safe for the patients surgery at the treatment of different forms of myasthenia.
M. B. Skvortsov, A. I. Smolin
doaj
Thymectomy in ocular myasthenia gravis—prognosis and risk factors analysis
Background Several retrospective studies have identified risk factors associated with ocular myasthenia gravis (OMG) generalization in non-surgical patients. However, the outcomes of OMG after thymectomy have not been investigated fully. This study aimed
Jinwei Zhang+6 more
doaj +1 more source