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YAP1-MAML2 Fusion as a Diagnostic Biomarker for Metaplastic Thymoma
BackgroundMetaplastic thymoma is a very rare tumor with only a few case reports documented in literature. Hence, its molecular features have not been well explored.Material and MethodsSeventeen specimens of metaplastic thymoma were sequenced and ...
Jikai Zhao+5 more
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Thymoma calcification: Is it clinically meaningful? [PDF]
Among anterior mediastinal lesions, thymoma is the most common. Thymomas are tumors of thymic epithelial cell origin that are distinguished by inconsistent histological and biologic behavior.
Alkaied Homam+4 more
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Paraneoplastic pemphigus regression after thymoma resection [PDF]
Background Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. Case presentation A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported ...
Stergiou Eleni+7 more
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Genome-wide genetic aberrations of thymoma using cDNA microarray based comparative genomic hybridization [PDF]
Background Thymoma is a heterogeneous group of tumors in biology and clinical behavior. Even though thymoma is divided into five subgroups following the World Health Organization classification, the nature of the disease is mixed within the subgroups ...
Park Chan+7 more
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D. Weissberg, M. Goldberg, F.G. Pearson
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B cell deficiency in thymoma tissues of Good’s syndrome patients [PDF]
Objectives Good’s syndrome (GS) is a rare secondary immunodeficiency which is characterized by hypogammaglobulinemia and thymoma. This study aims to investigate the expression and distribution of B cells in thymoma tissue, given that B cells had been ...
Junwu Zhang+4 more
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Thymomas are a heterogeneous group of tumors arising from the epithelium of the thymus. They are categorized by the proportion of neoplastic epithelia to lymphocytes and by the degree of cytologic atypia. Thymomas constitute 0.2-1.5% of all malignancies and nearly all occur in patients over 20 years.
Chand, Momal Tara+4 more
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Downregulation of HMGB1 in thymoma cells affects T cell differentiation
Introduction: Thymoma is the most common anterior mediastinal tumor and is closely associated with myasthenia gravis (MG). Our previous study showed that the expression of Th17 cells increased and the expression of Treg decreased in MG-associated thymoma
Jian Li+5 more
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Case Report: MDM4 Amplified in a Thymoma Patient With Autoimmune Enteropathy and Myocarditis
IntroductionThymoma is a type of mediastinal malignant tumors which always associated with autoimmune diseases. Although surgery is the predominant treatment method for thymoma, the pathogenesis of thymoma and thymoma-associated autoimmune diseases is ...
Xin Du+6 more
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Coexistence of Thymus and Colon Adenocarcinoma: A Case Report
Thymoma is a very rare tumor with a rate of 1.7 per million. Thymoma often occurs between the ages of 35-70. Thymoma is frequently located in the anterior mediastinum. Patients with thymoma often do not cause symptoms clinically.
Muhammed Selim Bodur+8 more
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