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YAP1-MAML2 Fusion as a Diagnostic Biomarker for Metaplastic Thymoma
Frontiers in Oncology, 2021 BackgroundMetaplastic thymoma is a very rare tumor with only a few case reports documented in literature. Hence, its molecular features have not been well explored.Material and MethodsSeventeen specimens of metaplastic thymoma were sequenced and ...
Jikai Zhao +5 more
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Good’s syndrome revealed by recurrent sigmoid diverticulitis [PDF]
European Journal of Case Reports in Internal MedicineThymus is a primary lymphoid organ whose main function is the education of the T lymphocytes. Thymoma is uncommon neoplasia derived from epithelial cells of the thymus. Patients with thymoma frequently present with autoimmune disorders, mostly myasthenia
Hassene Attout +4 more
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The Annals of Thoracic Surgery, 1973 D. Weissberg, M. Goldberg, F.G. Pearson
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Autopsy Case Reports, 2021 Thymomas are a heterogeneous group of tumors arising from the epithelium of the thymus. They are categorized by the proportion of neoplastic epithelia to lymphocytes and by the degree of cytologic atypia. Thymomas constitute 0.2-1.5% of all malignancies and nearly all occur in patients over 20 years.
Chand, Momal Tara +4 more
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Downregulation of HMGB1 in thymoma cells affects T cell differentiation
Central European Journal of Immunology, 2023 Introduction: Thymoma is the most common anterior mediastinal tumor and is closely associated with myasthenia gravis (MG). Our previous study showed that the expression of Th17 cells increased and the expression of Treg decreased in MG-associated thymoma
Jian Li +5 more
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Case Report: MDM4 Amplified in a Thymoma Patient With Autoimmune Enteropathy and Myocarditis
Frontiers in Endocrinology, 2021 IntroductionThymoma is a type of mediastinal malignant tumors which always associated with autoimmune diseases. Although surgery is the predominant treatment method for thymoma, the pathogenesis of thymoma and thymoma-associated autoimmune diseases is ...
Xin Du +6 more
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Coexistence of Thymus and Colon Adenocarcinoma: A Case Report
Van Tıp Dergisi, 2021 Thymoma is a very rare tumor with a rate of 1.7 per million. Thymoma often occurs between the ages of 35-70. Thymoma is frequently located in the anterior mediastinum. Patients with thymoma often do not cause symptoms clinically.
Muhammed Selim Bodur +8 more
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Identification of differentially expressed circular RNAs associated with thymoma
Thoracic Cancer, 2021 Background Thymomas and thymic carcinomas are the most common tumor types among anterior mediastinal lesions. However, the relationship between molecular aberrations and thymoma patients are poorly understood, especially abnormal changes in the ...
Qingjun Wu +8 more
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Internalization of IL-1 is required for IL-2 gene activation in EL4 thymoma cells [PDF]
, 1989 Werner Falk +4 more
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Immunotherapy for thymoma [PDF]
Journal of Thoracic Disease, 2020 Thymic epithelial tumors (TETs) are rare thymic neoplasms. There are approximately 1.5 cases per million TETs per year. They are the most common anterior mediastinal tumors in adults. Due to limited activity of available treatment options novel strategies and treatment options are needed and treatment with immune checkpoint inhibitors is an attractive ...
Kristina Krpina +7 more
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