Results 51 to 60 of about 338,057 (225)

Characterization of IL-10-producing regulatory B cells in thymoma

Autoimmunity, 2022
Background Regulatory B cells (Bregs) are a subset of B cells that secrete interleukin 10 (IL-10) and play a vital role in suppressing the immune response. The aim of this study was to evaluate the proportion of Bregs in patients with thymoma.
Fangnan Lin, Hailong You, Xiwen Cao, Tingting Li, Xiaodong Hong, Jinli Yang, Peng Huo, Jialin Li, Wei Liu, Yanfang Jiang   +9 more
doaj   +1 more source

Management of Refractory Thymoma‐Associated Myasthenia Gravis With Sequential FcRn Antagonist and Complement Inhibition Combined With Resection of Pleural Dissemination

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Myasthenia gravis (MG) associated with disseminated thymoma is often refractory to conventional treatments due to continuous autoantibody production. The optimal treatment strategy, particularly the combination of complement component 5 (C5) inhibitor, neonatal Fc receptor (FcRn) antagonist, and surgical resection in thymoma‐associated ...
Hiroyuki Takenaka, Madoka Iida, Yuki Fukami, Masahisa Katsuno   +3 more
wiley   +1 more source

Purulent pericarditis in advanced thymoma: A case report

Radiology Case Reports, 2022
Thymoma is the most common primary anterior mediastinum mass with various clinical manifestations, and one of the manifestations is pericardial effusion.
Jordan Bakhriansyah, MD, I Gede Parama Gandi Semita, MD, I Gde Rurus Suryawan, MD, Yusuf Azmi, MD, Irfan Deny Sanjaya, MD, Risma Ikawaty, MD, David Nugraha, BM, Firas Farisi Alkaff, MD   +7 more
doaj   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Thymoma with chronic diarrhea

, 2007
Thymoma associated with hypogammaglobulinemia and profound susceptibility to recurrent and serious infections was first reported by Good in 1954, after whom it was named as Good's syndrome.
Kaynak, Kamil, CETIN, Sibel Erdamar, YANMAZ, Teoman, Ozguroglu, Mustafa, Akman, Canan, TURNA, Hande, Celik, AYKUT, Oz, Buge, Yildiz, Ozcan, ÇELİK, AYKUT FERHAT   +9 more
core   +1 more source

Comparison of Efficacy and Safety of Platinum-Based Chemotherapy as First-Line Therapy between B3 Thymoma and Thymic Carcinoma

Current Oncology, 2022
Background: B3 type thymoma is defined as a well-differentiated thymic carcinoma and is similar to a thymic carcinoma. However, the differences between them are not well defined.
Yue Hao, Jinfei Si, Jianan Jin, Jingwen Wei, Jing Xiang, Chunwei Xu, Zhengbo Song   +6 more
doaj   +1 more source

Refining the treatment of immune checkpoint inhibitor–associated myocarditis: Challenges, innovations and rechallenge considerations

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitor (ICI)‐associated myocarditis has emerged as a severe and clinically complex immune‐related toxicity that poses significant challenges for therapeutic decision‐making in routine cardio‐oncological care. High‐dose corticosteroids remain the first‐line therapy, yet their timing, dosage and tapering require careful clinical ...
Raluca I. Mincu, Lisa Zimmer, Dimitra Vlachopoulou, Elias Haj‐Yehia, Julia Hoffmann, Lars Michel, Elisabeth Livingstone, Dirk Schadendorf, Alpaslan Tasdogan, Matthias Totzeck, Tienush Rassaf   +10 more
wiley   +1 more source

Autoimmune hepatitis : an uncommon presentation of thymoma

, 2016
Purpose: In a substantial proportion of patients with thymoma, many different types of paraneoplastic syndromes are observed. The association between thymoma and autoimmune liver diseases, however, has been found in very few cases. Methods: We report the
P. Mendogni, F. Minonzio, I. Righi, A. Palleschi, FUSCO, NICOLA, D. Tosi, M. Nosotti, L. Rosso   +7 more
core   +1 more source

Genome-wide genetic aberrations of thymoma using cDNA microarray based comparative genomic hybridization

BMC Genomics, 2007
Background Thymoma is a heterogeneous group of tumors in biology and clinical behavior. Even though thymoma is divided into five subgroups following the World Health Organization classification, the nature of the disease is mixed within the subgroups ...
Park Chan, Seo Min, Kim Sang, Jeung Hei, Yang Woo, Lee Gui, Chung Hyun, Rha Sun   +7 more
doaj   +1 more source

Pleiotropic Roles of FBXO11 in Tumorigenesis: Implications for Targeted Therapy

Cancer Science, Volume 117, Issue 11, Page 2910-2923, November 2026.
This complex comprises of scaffold CUL1, SKP1, RBX1 and FBXO11 receptor. The substrate is phosphorylated by specific kinase enzyme and recognized by the substrate recognition domain. FBXO11 targets numerous substrates for ubiquitination and degradation, FBXO11 substrates mainly include Snail, ZEB1, p53, BCL6, CDT2, CIITA, Cdc25a, hnRNPA2B1, SAMD1 and ...
Yuqi Zhang, Changyi Fan, Shiheng Chen, Tianyue Lu, Yuanyuan Li, Feng Du, Shanshan Wang   +6 more
wiley   +1 more source