Abstract As crewed space missions set course for the Moon and beyond, astronauts will experience prolonged exposure to Galactic Cosmic Rays (GCR) and potentially intense Solar Proton Events (SPEs), both of which pose significant short‐ and long‐term health risks.
Sylvain Blunier +4 more
wiley +1 more source
Immunosuppression after pediatric liver transplantation may lead to early and prolonged acute thymic involution: findings from a pilot longitudinal study. [PDF]
Costaguta G +8 more
europepmc +1 more source
Ectopic Cervical Thymoma with Myasthenia Gravis and Pure Red Cell Aplasia: A Case Report. [PDF]
Narusawa E +9 more
europepmc +1 more source
Background and Purpose Oxidative stress plays a critical role in the pathophysiology of various diseases, yet current methods for its non‐invasive detection remain limited. This study aimed to systematically validate a superoxide‐selective PET tracer, [18F]FPBT, for the early diagnosis and therapeutic monitoring of oxidative stress‐related conditions ...
Hua Zhang +10 more
wiley +1 more source
Recent developments in salivary gland pathology after the WHO 2024 classification: new developments in existing entities and evolving new entities. [PDF]
Skálová A +9 more
europepmc +1 more source
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Integrin α7-Driven Senescence-Associated Follicular Helper T Cell Adhesion Induces Tertiary Lymphoid Structures in Nishiura Mice. [PDF]
Nishiura H +7 more
europepmc +1 more source
The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald +6 more
wiley +1 more source
Oxidative Stress, Post‐Translational Modifications, and Type 1 Diabetes Pathogenesis
ABSTRACT Type 1 diabetes (T1D) is an organ‐specific autoimmune disease that destroys insulin‐producing beta‐cells. Insulin is a vital hormone for regulating glycemia that often undergoes post‐translational modifications during processing from pre‐proinsulin to biologically active insulin.
Colleen J. Winstead +2 more
wiley +1 more source

