Results 1 to 10 of about 191,183 (217)

Thymus and autoimmunity [PDF]

open access: yesSeminars in Immunopathology, 2021
AbstractThe thymus prevents autoimmune diseases through mechanisms that operate in the cortex and medulla, comprising positive and negative selection and the generation of regulatory T-cells (Tregs). Egress from the thymus through the perivascular space (PVS) to the blood is another possible checkpoint, as shown by some autoimmune/immunodeficiency ...
Alexander Marx   +6 more
openaire   +3 more sources

Near-isotropic, reconstructed volume electron microscopy (FIB-SEM) of P7 mouse thymus (jrc_mus-thymus-1) [PDF]

open access: yes, 2023
Sample: Thymus tissue from a wild-type, postnatal day 7 mouse, strain: C57BL/6J from Jackson LabSample Description: A dataset featuring isotropic 3D electron microscopy data of the mouse thymus (jrc_mus-thymus-1). The sample was obtained from a wild-type
Stephan Preibisch (12975014)   +5 more
core   +1 more source

The Role of Proteasomes in the Thymus

open access: yesFrontiers in Immunology, 2021
The thymus provides a microenvironment that supports the generation and selection of T cells. Cortical thymic epithelial cells (cTECs) and medullary thymic epithelial cells (mTECs) are essential components of the thymic microenvironment and present MHC ...
Melina Frantzeskakis   +2 more
doaj   +1 more source

Gender Disparity Impacts on Thymus Aging and LHRH Receptor Antagonist-Induced Thymic Reconstitution Following Chemotherapeutic Damage

open access: yesFrontiers in Immunology, 2020
One of the main consequences of thymus aging is the decrease in naïve T cell output. This condition accelerates at the onset of puberty, and presents as a major clinical complication for cancer patients who require cytoablative therapy. Specifically, the
Michael Ly Hun   +5 more
doaj   +1 more source

Therapeutic Efficacy of Flavonoids in Allergies: A Systematic Review of Randomized Controlled Trials

open access: yesJournal of Immunology Research, 2022
Objective. To assess the clinical efficacy of flavonoid supplements on allergic diseases. Design. Systematic review. Data Sources. MEDLINE/PubMed, Scopus, Web of Science, and Embase databases were searched from inception to September 2021.
Poliana Guiomar de Almeida Brasiel   +4 more
doaj   +1 more source

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

open access: yesFrontiers in Endocrinology, 2020
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the regulation of metabolic, endocrine and immune functions.
Ygor Parladore Silva   +2 more
doaj   +1 more source

HGF potentiates extracellular matrix-driven migration of human myoblasts: involvement of matrix metalloproteinases and MAPK/ERK pathway

open access: yesSkeletal Muscle, 2017
Background The hepatocyte growth factor (HGF) is required for the activation of muscle progenitor cells called satellite cells (SC), plays a role in the migration of proliferating SC (myoblasts), and is present as a soluble factor during muscle ...
Mariela Natacha González   +6 more
doaj   +1 more source

Zika virus infects human blood mononuclear cells

open access: yesBMC Infectious Diseases, 2019
Background Zika virus (ZIKV) infection gained public health concern after the 2015 outbreak in Brazil, when microcephaly rates increased in babies born from infected mothers.
Carolina V. Messias   +10 more
doaj   +1 more source

Lack of Galectin-3 Disrupts Thymus Homeostasis in Association to Increase of Local and Systemic Glucocorticoid Levels and Steroidogenic Machinery

open access: yesFrontiers in Endocrinology, 2018
Maintenance of thymus homeostasis is a delicate interplay involving hormones, neurotransmitters and local microenvironmental proteins, as well as saccharides, acting on both thymocytes and stromal cells.
Ednéa Oliveira-de-Abreu   +14 more
doaj   +1 more source

Chemical Composition of Essential Oilsof Thymus and Mentha Speciesand Their Antifungal Activities [PDF]

open access: yes, 2009
The potential antifungal effects of Thymus vulgaris L., Thymus tosevii L., Mentha spicata L., and Mentha piperita L. (Labiatae) essential oils and their components against 17 micromycetal food poisoning, plant, animal and human pathogens are presented ...
Marin, P.D.   +31 more
core   +1 more source

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