T-cells and transplantation tolerance in Thymectomised Xenopus implanted with foreign thymus [PDF]
, 1990 This thesis investigates the expression of a T-cell differentiation antigen, (XTLA- 1), in various strains and species of Xenopus, and demonstrates the effect of early-thymectomy, (by microcautery), on XTLA-1 expression.
Varley, C.A, Varley, Claire Alison
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Reaggregate Thymus Cultures [PDF]
, 2008 In the thymus, immature CD4+8+ thymocytes expressing randomly rearranged T-cell receptor alpha- and b-chain genes undergo positive and negative selection events based on their ability to recognize self-peptide/major histocompatibility complex (MHC ...
Andrea White +5 more
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Archives of Internal Medicine, 1917 "Persistent thymus" has been a term in the literature, though a term about which much skepticism has gathered. But it is gradually becoming established as a fact that the thymic parenchyma persists throughout life, and that this parenchyma may become reactivated to the extent that its secretion influences the endocrine equilibrium. The causes of such a
openaire +2 more sources
Characterization of the spatio-temporal dynamics in thymic epithelial development [PDF]
, 2015 The work presented in this thesis is centered on the development and maturation of the epithelial compartment in the murine thymus and consequently its functional capacity to promote normal thymopoiesis. Two main aspects have been investigated in depth:
Mayer, Carlos E.
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Phytochemical screening, antioxidant and antibacterial activity of Thymus (vulgaris, algeriensis and brousonettii) extracts [PDF]
Herba PolonicaThis study aimed to explore the biological properties and secondary metabolites present in extracts of Thymus species, including Thymus vulgaris, Thymus algeriensis, and Thymus broussonettii.
Mohamed Hatim Labiad +5 more
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Regulation of γδ T Cell Effector Diversification in the Thymus
Frontiers in Immunology, 2020 γδ T cells are the first T cell lineage to develop in the thymus and take up residence in a wide variety of tissues where they can provide fast, innate-like sources of effector cytokines for barrier defense.
Morgan E. Parker, Maria Ciofani
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Regulation of IkappaB Protein Expression by Early Gestation in the Thymus of Ewes
Veterinary Sciences, 2023 The thymus is an essential component of maternal immune systems that play key roles in recognizing the placenta as immunologically foreign. The inhibitor of the NF-κB (IκB) family has essential effects on the NF-κB pathway; however, it is unclear whether
Yao Meng +5 more
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Automatic nuclei segmentations in near-isotropic, reconstructed volume electron microscopy (FIB-SEM) of P7 mouse thymus (jrc_mus-thymus-1) model [PDF]
Model description: Cellpose 2.0 was trained on nuclei from 20 2D slices from jrc_mus-thymus-1.Architecture: Cellpose 2.0Input voxel size (nm): 128 x 128 x 128 (X, Y, Z)Output voxel size (nm): 128 x 128 x 128 (X, Y, Z)Classes trained on: NucleusGPU: RTX ...
Aubrey Weigel (9302851) +1 more
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Delta-like 4 is indispensable in thymic environment specific for T cell development. [PDF]
, 2008 The thymic microenvironment is required for T cell development in vivo. However, in vitro studies have shown that when hematopoietic progenitors acquire Notch signaling via Delta-like (Dll)1 or Dll4, they differentiate into the T cell lineage in the ...
Holländer, Georg +30 more
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Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development [PDF]
, 2011 Dendritic cells (DCs) in the thymus (tDCs) are predominantly accumulated in the medulla and contribute to the establishment of self-tolerance. However, how the medullary accumulation of tDCs is regulated and involved in self-tolerance is unclear. We show
Ishimaru, N. +36 more
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