Results 21 to 30 of about 208,657 (313)

Neuroendocrine Control of Macrophage Development and Function

Frontiers in Immunology, 2018
Macrophages carry out numerous physiological activities that are essential for both systemic and local homeostasis, as well as innate and adaptive immune responses. Their biology is intricately regulated by hormones, neuropeptides, and neurotransmitters,
Arnon Dias Jurberg, Arnon Dias Jurberg, Vinícius Cotta-de-Almeida, Vinícius Cotta-de-Almeida, Jairo Ramos Temerozo, Jairo Ramos Temerozo, Wilson Savino, Wilson Savino, Dumith Chequer Bou-Habib, Dumith Chequer Bou-Habib, Ingo Riederer, Ingo Riederer   +11 more
doaj   +1 more source

Chemical composition of essential oil for Thymus population from Albania

Zaštita Materijala, 2020
This study presents data about chemical composition of essential oils for Thymus populations from the Albania. The genus Thymus contains about 350 species of aromatic plants in the family Lamiaceae.
Jonida Salihila, Dorina Shengjergji, Dhimiter Peci, Aida Dervishi   +3 more
doaj   +1 more source

A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation

eLife, 2021
Ataxia Telangiectasia (A-T) and Ataxia with Ocular Apraxia Type 1 (AOA1) are devastating neurological disorders caused by null mutations in the genome stability genes, A-T mutated (ATM) and Aprataxin (APTX), respectively.
Harvey Perez, May F Abdallah, Jose I Chavira, Angelina S Norris, Martin T Egeland, Karen L Vo, Callan L Buechsenschuetz, Valentina Sanghez, Jeannie L Kim, Molly Pind, Kotoka Nakamura, Geoffrey G Hicks, Richard A Gatti, Joaquin Madrenas, Michelina Iacovino, Peter J McKinnon, Paul J Mathews   +16 more
doaj   +1 more source

Oral Versus Intragastric Inoculation: Similar Pathways of Trypanosoma cruzi Experimental Infection? From Target Tissues, Parasite Evasion, and Immune Response

Frontiers in Immunology, 2018
Currently, oral infection is the most frequent transmission mechanism of Chagas disease in Brazil and others Latin American countries. This transmission pathway presents increased mortality rate in the first 2 weeks, which is higher than the calculated ...
Juliana Barreto de Albuquerque, Danielle Silva dos Santos, Jens V. Stein, Juliana de Meis, Juliana de Meis   +4 more
doaj   +1 more source

Oral Route Driven Acute Trypanosoma cruzi Infection Unravels an IL-6 Dependent Hemostatic Derangement

Frontiers in Immunology, 2019
Oral transmission of Trypanosoma cruzi, the etiologic agent of Chagas disease, is presently the most important route of infection in Brazilian Amazon.
Dina Antunes, Dina Antunes, Alessandro Marins-Dos-Santos, Alessandro Marins-Dos-Santos, Mariana Tavares Ramos, Mariana Tavares Ramos, Barbara Angelica S. Mascarenhas, Barbara Angelica S. Mascarenhas, Carlos José de Carvalho Moreira, Désio Aurélio Farias-de-Oliveira, Désio Aurélio Farias-de-Oliveira, Wilson Savino, Wilson Savino, Robson Q. Monteiro, Juliana de Meis, Juliana de Meis   +15 more
doaj   +1 more source

The Neuropeptides Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-Activating Polypeptide Control HIV-1 Infection in Macrophages Through Activation of Protein Kinases A and C

Frontiers in Immunology, 2018
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) are highly similar neuropeptides present in several tissues, endowed with immunoregulatory functions and other systemic effects.
Jairo R. Temerozo, Jairo R. Temerozo, Suwellen S. D. de Azevedo, Daniella B. R. Insuela, Rhaíssa C. Vieira, Pedro L. C. Ferreira, Vinícius F. Carvalho, Vinícius F. Carvalho, Gonzalo Bello, Dumith Chequer Bou-Habib, Dumith Chequer Bou-Habib   +10 more
doaj   +1 more source

Effect of GnRH immunocastration on immune function in male rats

Frontiers in Immunology, 2023
The present study aimed to reveal the effects of immunocastration on the development of the immune system in rats. Seventy rats were randomly assigned into two groups: Control (n = 35) and immunized (n = 35).
Fuqiang Pan, Huiting Du, Weiguo Tian, Huihui Xie, Bochao Zhang, Wanzhen Fu, Yunsheng Li, Yunsheng Li, Yunsheng Li, Yinghui Ling, Yinghui Ling, Yinghui Ling, Yunhai Zhang, Yunhai Zhang, Yunhai Zhang, Fugui Fang, Fugui Fang, Fugui Fang, Ya Liu, Ya Liu, Ya Liu   +20 more
doaj   +1 more source

Metabolic Regulation of Thymic Epithelial Cell Function

Frontiers in Immunology, 2021
The thymus is the primary site of T lymphocyte development, where mutually inductive signaling between lymphoid progenitors and thymic stromal cells directs the progenitors along a well-characterized program of differentiation.
Manpreet K. Semwal, Nicholas E. Jones, Ann V. Griffith   +2 more
doaj   +1 more source

Role of Hormonal Circuitry Upon T Cell Development in Chagas Disease: Possible Implications on T Cell Dysfunctions

Frontiers in Endocrinology, 2018
T cell response plays an essential role in the host resistance to infection by the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease.
Ana Rosa Pérez, Alexandre Morrot, Alexandre Morrot, Vinicius Frias Carvalho, Vinicius Frias Carvalho, Juliana de Meis, Juliana de Meis, Wilson Savino, Wilson Savino   +8 more
doaj   +1 more source

Thymic Epithelial Cell Alterations and Defective Thymopoiesis Lead to Central and Peripheral Tolerance Perturbation in MHCII Deficiency

Frontiers in Immunology, 2021
Major Histocompatibility Complex (MHC) class II (MHCII) deficiency (MHCII-D), also known as Bare Lymphocyte Syndrome (BLS), is a rare combined immunodeficiency due to mutations in genes regulating expression of MHCII molecules.
Francesca Ferrua, Francesca Ferrua, Francesca Ferrua, Ileana Bortolomai, Elena Fontana, Elena Fontana, Dario Di Silvestre, Rosita Rigoni, Rosita Rigoni, Genni Enza Marcovecchio, Elena Draghici, Francesca Brambilla, Maria Carmina Castiello, Maria Carmina Castiello, Gloria Delfanti, Despina Moshous, Despina Moshous, Capucine Picard, Capucine Picard, Capucine Picard, Tom Taghon, Victoria Bordon, Ansgar S. Schulz, Catharina Schuetz, Catharina Schuetz, Silvia Giliani, Annarosa Soresina, Andrew R. Gennery, Andrew R. Gennery, Sara Signa, Sara Signa, Blachy J. Dávila Saldaña, Ottavia M. Delmonte, Luigi D. Notarangelo, Chaim M. Roifman, Pietro Luigi Poliani, Paolo Uva, Pier Luigi Mauri, Anna Villa, Anna Villa, Marita Bosticardo, Marita Bosticardo   +41 more
doaj   +1 more source