Results 31 to 40 of about 307,196 (302)

Growth of donor-derived dendritic cells from the bone marrow of murine liver auograft recipients in response to granulocyte/macrophage colony-stimulating factor [PDF]

, 1995
Allografts of the liver, which has a comparatively heavy leukocyte content compared with other vascularized organs, are accepted permanently across major histocompatibility complex barriers in many murine strain combinations without immunosuppressive ...
Fu, F, Fung, JJ, Lu, L, McCaslin, D, Qian, S, Rao, AS, Rudert, WA, Starzl, TE, Thomson, AW, Trucco, M   +9 more
core   +1 more source

Impaired thymic iNKT cell differentiation at early precursor stage in murine haploidentical bone marrow transplantation with GvHD

Frontiers in Immunology, 2023
IntroductionEarly recovery of donor-derived invariant natural killer T (iNKT) cells are associated with reduced risk of graft-versus-host disease (GvHD) and overall survival.
Weijia Zhao, Yujia Wang, Xinwei Zhang, Jie Hao, Kunshan Zhang, Xiaojun Huang, Yingjun Chang, Hounan Wu, Rong Jin, Qing Ge, Qing Ge   +10 more
doaj   +1 more source

High efficiency transfection of thymic epithelial cell lines and primary thymic epithelial cells by Nucleofection [PDF]

, 2011
Thymic epithelial cells (TECs) are required for the development and differentiation of T cells and are sufficient for the positive and negative selection of developing T cells.
Brian G. Condie, Qiaozhi Wei, Richard T. O'   +2 more
core   +2 more sources

Oral Versus Intragastric Inoculation: Similar Pathways of Trypanosoma cruzi Experimental Infection? From Target Tissues, Parasite Evasion, and Immune Response

Frontiers in Immunology, 2018
Currently, oral infection is the most frequent transmission mechanism of Chagas disease in Brazil and others Latin American countries. This transmission pathway presents increased mortality rate in the first 2 weeks, which is higher than the calculated ...
Juliana Barreto de Albuquerque, Danielle Silva dos Santos, Jens V. Stein, Juliana de Meis, Juliana de Meis   +4 more
doaj   +1 more source

Improving thymus implantation for congenital athymia with interleukin‐7

Clinical & Translational Immunology, 2023
Objectives Thymus implantation is a recently FDA‐approved therapy for congenital athymia. Patients receiving thymus implantation develop a functional but incomplete T cell compartment.
Hyunjung Min, Laura A Valente, Li Xu, Shane M O'Neil, Lauren R Begg, Joanne Kurtzberg, Anthony J Filiano   +6 more
doaj   +1 more source

A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation

eLife, 2021
Ataxia Telangiectasia (A-T) and Ataxia with Ocular Apraxia Type 1 (AOA1) are devastating neurological disorders caused by null mutations in the genome stability genes, A-T mutated (ATM) and Aprataxin (APTX), respectively.
Harvey Perez, May F Abdallah, Jose I Chavira, Angelina S Norris, Martin T Egeland, Karen L Vo, Callan L Buechsenschuetz, Valentina Sanghez, Jeannie L Kim, Molly Pind, Kotoka Nakamura, Geoffrey G Hicks, Richard A Gatti, Joaquin Madrenas, Michelina Iacovino, Peter J McKinnon, Paul J Mathews   +16 more
doaj   +1 more source

Murine terminal deoxynucleotidyl transferase: cellular distribution and response to cortisone [PDF]

, 1975
The mouse thymus contains two forms of terminal deoxynucleotidyl transferase (TdT) which are distinguishable by the salt concentration necessary to elute them from a phosphocellulose column, by their distrubtion among the thymocyte subpopulations, and by
Baltimore, David, Kung, Patrick C., McCaffrey, Ronald P., Silverstone, Allen E.   +3 more
core   +1 more source

Oral Route Driven Acute Trypanosoma cruzi Infection Unravels an IL-6 Dependent Hemostatic Derangement

Frontiers in Immunology, 2019
Oral transmission of Trypanosoma cruzi, the etiologic agent of Chagas disease, is presently the most important route of infection in Brazilian Amazon.
Dina Antunes, Dina Antunes, Alessandro Marins-Dos-Santos, Alessandro Marins-Dos-Santos, Mariana Tavares Ramos, Mariana Tavares Ramos, Barbara Angelica S. Mascarenhas, Barbara Angelica S. Mascarenhas, Carlos José de Carvalho Moreira, Désio Aurélio Farias-de-Oliveira, Désio Aurélio Farias-de-Oliveira, Wilson Savino, Wilson Savino, Robson Q. Monteiro, Juliana de Meis, Juliana de Meis   +15 more
doaj   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Oestrogen, an evolutionary conserved regulator of T cell differentiation and immune tolerance in jawed vertebrates? [PDF]

, 2018
In teleosts, as in mammals, the immune system is tightly regulated by sexual steroid hormones, such as oestrogens. We investigated the effects of 17β-oestradiol on the expression of several genes related to T cell development and resulting T cell ...
Duflot, Aurélie, Farcy, Emilie, Knigge, Thomas, Monsinjon, Tiphaine, Paiola, Matthieu, Pinto, Patricia IS   +5 more
core   +3 more sources