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The thymus gland is highly valuable, due to its functions as a part of the neuroendocrine system as well as its actions to provide a primary lymphoid microenvironment that efficiently carries T-cell differentiation and selection. This book begins with an
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Pictorial essay. Pathology of the thymus on CT-imaging.
A number of masses arise in relation to the thymus. The radiologist has an important role regarding the differential diagnosis between non-tumoral thymic pathology and malignant thymic tumors.
R Peters +3 more
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Refined, automatic nuclei segmentations in near-isotropic, reconstructed volume electron microscopy (FIB-SEM) of P7 mouse thymus (jrc_mus-thymus-1) [PDF]
Segmentation description: Nuclei segmentations in jrc_mus-thymus-1 using Cellpose 2.0 with minimal manual corrections. Software: Cellpose 2.0 Software DOI: https://doi.org/10.1038/s41592-022-01663-4 GPU: RTX A6000 RAM: 256.0 GiB Label voxel size (nm ...
Aubrey Weigel (9302851) +4 more
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Immunodeficiency in DiGeorge Syndrome and Options for Treating Cases with Complete Athymia. [PDF]
The commonest association of thymic stromal deficiency resulting in T-cell immunodeficiency is the DiGeorge syndrome (DGS). This results from abnormal development of the third and fourth pharyngeal arches and is most commonly associated with a ...
E. Graham Davies +2 more
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The thymoproteasome, a proteolytic complex uniquely expressed in cortical thymic epithelial cells (cTECs), governs the positive selection of CD8 T cells.
Mami Matsuda-Lennikov +14 more
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Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance
Summary: Medullary thymic epithelial cells (mTECs) are essential for the establishment of self-tolerance in T cells. Promiscuous gene expression by a subpopulation of mTECs regulated by the nuclear protein Aire contributes to the display of self-genomic ...
Aya Ushio +7 more
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Distinguishing T-lymphoblastic leukemia/lymphoma (T-ALL/T-LBL) from thymomas (especially B1 or B2 type) can be challenging particularly in limited trucut biopsy material where appreciating architecture is difficult or the background epithelial component ...
Divya Bansal +6 more
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Aberrant cervical thymus and the role of ultrasonography: A case report
Ectopic/aberrant cervical thymic tissue is a rare cause of neck mass and usually detected incidentally. Aberrant thymic tissue can occur anywhere in the course of thymic descent from the angle of the mandible to the superior mediastinum. We report
Emre Ünal +3 more
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Psychosocial factors are associated with the antibody response to both thymus-dependent and thymus-independent vaccines [PDF]
The present study examined the association between psychological stress, social support and antibody response to both thymus-dependent and thymus-independent vaccinations.
Ferraro, Alastair J +17 more
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Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation. [PDF]
Hematopoietic stem cell transplantation (HSCT) requires conditioning treatments such as irradiation, which leads to a severely delayed recovery of T cell immunity and constitutes a major complication of this therapy.
Linda Kenins +14 more
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