Results 71 to 80 of about 208,657 (313)
Psychosocial factors are associated with the antibody response to both thymus-dependent and thymus-independent vaccines [PDF]
, 2008 The present study examined the association between psychological stress, social support and antibody response to both thymus-dependent and thymus-independent vaccinations.
Ferraro, Alastair J +17 more
core +2 more sources
Advanced Science, EarlyView.ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐binding protein 3 (HS1BP3) is preferentially expressed in memory CD8+ T cells.
Siyang Wang +13 more
wiley +1 more source
Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection
Frontiers in Immunology, 2018 A family of transcription factors known as E proteins, and their antagonists, Id proteins, regulate T cell differentiation at critical developmental checkpoints.
Sumedha Roy +8 more
doaj +1 more source
Uremia-Associated Ageing of the Thymus and Adaptive Immune Responses
Toxins, 2020 Progressive loss of renal function is associated with a series of changes of the adaptive immune system which collectively constitute premature immunological ageing.
Michiel GH Betjes
doaj +1 more source
Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation [PDF]
, 2007 TCR signal strength is involved in many cell fate decisions in the T-cell lineage. Here, we show that transcriptional events induced by Hedgehog (Hh) signaling reduced TCR signal strength in mice.
Drakopoulou, E +7 more
core
Role of regulatory T cells in immune tolerance [PDF]
, 2009 In this present work, we investigated the role of dendritic cells (DC) and regulatory T cells (Treg) in immune tolerance as well as their potential in the treatment of autoimmune or graft versus host (GvH) diseases.
Swee, Lee Kim
core +1 more source
Advanced Science, EarlyView.Tendon interfascicular and fascicular matrix cells are isolated and cultured, revealing distinct phenotypes and mechanosensitive responses. Interfascicular matrix cells exhibit marked stiffness‐dependent phenotypic plasticity, whereas fascicular matrix cells remain comparatively stable.
S. E. Grossemy +10 more
wiley +1 more source
PPARgamma Deficiency Counteracts Thymic Senescence
Frontiers in Immunology, 2017 Thymic senescence contributes to increased incidence of infection, cancer and autoimmunity at senior ages. This process manifests as adipose involution. As with other adipose tissues, thymic adipose involution is also controlled by PPARgamma.
David Ernszt +10 more
doaj +1 more source
Advanced Science, EarlyView.After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin +9 more
wiley +1 more source
Intrathymic expression of Flt3 ligand enhances thymic recovery after irradiation. [PDF]
, 2008 Hematopoietic stem cell transplantation (HSCT) requires conditioning treatments such as irradiation, which leads to a severely delayed recovery of T cell immunity and constitutes a major complication of this therapy.
Linda Kenins +14 more
core +1 more source