Results 81 to 90 of about 307,196 (302)

Tomato protoplast DNA transformation: physical linkage and recombination of exogenous DNA sequences [PDF]

, 1987
Tomato protoplasts have been transformed with plasmid DNA's, containing a chimeric kanamycin resistance gene and putative tomato origins of replication.
A Crossway, A Deshayes, B Reiss, BR Thomas, C-L Hsiao, CP Meredith, DT Stinchcomb, EA Shahin, FA Krens, G Scangos, HC Birnboim, HE Ruley, I Potrykus, J Messing, J Paszkowski, Jacques Hille, JD Rochaix, K Struhl, K Wernars, KC Reed, KR Folger, M Koornneef, M Perucho, Maarten Jongsma, Maarten Koornneef, MG Murray, MW Bevan, O Smithies, P Zabel, Pim Zabel, PW Rigby, R Hain, R Peerbolte, RA Anderson, RD Shillito, S Kato, SN Cohen, T Maniatis, TL Adams   +38 more
core   +4 more sources

Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70 [PDF]

, 2018
Various subsets of invariant natural killer T (iNKT) cells with different cytokine productions develop in the mouse thymus, but the factors driving their differentiation remain unclear.
A Hutloff, AK Stanic, B San Luis, BB Au-Yeung, BB Au-Yeung, CQ Chu, D Davidson, DG Pellicci, DG Pellicci, DG Wei, DI Godfrey, EJ Wherry, F Scheuplein, F Scheuplein, FW McNab, G Anderson, G Fu, G Kollias, G Seumois, H Georgiev, H Watarai, HS Azzam, I Engel, I Engel, J Henao-Mejia, J Novak, J Zikherman, JL Matsuda, JL Matsuda, JM Mason, K Benlagha, K Hirota, K Oleinika, K Yamamoto, L Brossay, L Linsen, LH Mason, LM D'Cruz, M Cruz Tleugabulova, M Gaya, M Guma, M Hashimoto, M Kronenberg, M Zhu, MA Weinreich, MB Drennan, MC Leite-De-Moraes, MC Leite-De-Moraes, MI Zimmer, MP Seiler, N Bottini, N Sakaguchi, NA Nagarajan, R Genolet, RJ Martinez, S Akbulut, S Jung, S Picelli, S Sidobre, SE Levin, TN Newman, V Cerundolo, V Sivakumar, WY Lee, X Li, YJ Lee, YL Chiu   +66 more
core   +4 more sources

Id Proteins Suppress E2A-Driven Invariant Natural Killer T Cell Development prior to TCR Selection

Frontiers in Immunology, 2018
A family of transcription factors known as E proteins, and their antagonists, Id proteins, regulate T cell differentiation at critical developmental checkpoints.
Sumedha Roy, Amanda J. Moore, Cassandra Love, Anupama Reddy, Deepthi Rajagopalan, Sandeep S. Dave, Leping Li, Cornelis Murre, Yuan Zhuang   +8 more
doaj   +1 more source

Uremia-Associated Ageing of the Thymus and Adaptive Immune Responses

Toxins, 2020
Progressive loss of renal function is associated with a series of changes of the adaptive immune system which collectively constitute premature immunological ageing.
Michiel GH Betjes
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium

eLife
Thymus medulla epithelium establishes immune self-tolerance and comprises diverse cellular subsets. Functionally relevant medullary thymic epithelial cells (mTECs) include a self-antigen-displaying subset that exhibits genome-wide promiscuous gene ...
Izumi Ohigashi, Andrea J White, Mei-Ting Yang, Sayumi Fujimori, Yu Tanaka, Alison Jacques, Hiroshi Kiyonari, Yosuke Matsushita, Sevilay Turan, Michael C Kelly, Graham Anderson, Yousuke Takahama   +11 more
doaj   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

The effect of helper virus on Abelson virus-induced transformation of lymphoid cells [PDF]

, 1978
Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses.
Baltimore, David, Rosenberg, Naomi
core   +2 more sources

PPARgamma Deficiency Counteracts Thymic Senescence

Frontiers in Immunology, 2017
Thymic senescence contributes to increased incidence of infection, cancer and autoimmunity at senior ages. This process manifests as adipose involution. As with other adipose tissues, thymic adipose involution is also controlled by PPARgamma.
David Ernszt, David Ernszt, Krisztina Banfai, Krisztina Banfai, Zoltan Kellermayer, Attila Pap, Janet M. Lord, Judit E. Pongracz, Judit E. Pongracz, Krisztian Kvell, Krisztian Kvell   +10 more
doaj   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source