Results 101 to 110 of about 208,657 (313)

Distribution of T-lymphocyte subsets in porcine lymphoid tissues [PDF]

open access: yes, 1987
The distribution of the functional subsets of porcine T cells, the cytolytic/suppressor (Tc/s) and the helper/inducer (Th/i) cells was studied in cryostat sections of thymus, lymph nodes, tonsils, Peyer's patches, spleen and liver using the indirect ...
Saalmüller, Armin   +4 more
core   +1 more source

Antibodies to acetylcholine receptor in parous women with myasthenia: evidence for immunization by fetal antigen [PDF]

open access: yes, 2002
The weakness in myasthenia gravis (MG) is mediated by autoantibodies against adult muscle acetylcholine receptors (AChR) at the neuromuscular junction; most of these antibodies also bind to fetal AChR, which is present in the thymus.
Wilcox, Nick   +13 more
core   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub   +3 more
wiley   +1 more source

Aspectos subjetivos do morar e trabalhar na mesma comunidade: a realidade vivenciada pelo agente comunitário de saúde

open access: yesInterface: Comunicação, Saúde, Educação
O Agente Comunitário de Saúde (ACS) é o elo entre comunidade e sistema de saúde no Programa Saúde da Família (PSF), sendo o único trabalhador que obrigatoriamente reside na comunidade onde trabalha.
Tatiana de Andrade Jardim, Selma Lancman
doaj  

Kin discrimination in plants: overview and implications for population and community ecology

open access: yesBiological Reviews, EarlyView.
ABSTRACT Following the discovery of identity discrimination, particularly self and kin discrimination amongst plant competitors, research on interplant interactions has advanced significantly within plant physiology and evolutionary ecology. This review synthesizes current knowledge on how both self and kin discrimination influence plant growth ...
Akira Yamawo
wiley   +1 more source

Viscosity of concentrated mRNA solutions: Implications for downstream processing

open access: yesBiotechnology Progress, EarlyView.
Abstract Messenger RNA (mRNA) therapeutics can be used to protect against infectious disease and for the treatment of cancers and genetic disorders. In order to obtain the desired therapeutic dosage, it is necessary to concentrate the mRNA to levels where the viscosity of the mRNA solutions can become significant.
Amin Javidanbardan   +3 more
wiley   +1 more source

Peculiarities of lymphocytes emigration from newborn thymus

open access: yesPatologìâ, 2017
Introduction. Mechanisms of mass lymphocytes’ emigration from thymus are still unclear. The process of lymphocytes migration and mechanisms, which provide it, form one of the important problems of immunomorphology.
O. A. Grygorieva, O. A. Apt
doaj   +1 more source

Isolation and Chemical Profile of Thymus Serpyllum L. and Lavandula Angustifolia Mill. Essential Oils [PDF]

open access: yes, 2017
Aim of this study was to isolate essential oil from two different plants, Thymus serpyllum L. and Lavandula angustifolia Mill., as well to investigate their chemical composition. Essential oil was isolated by hydrodistillation, while chemical composition
Radojkovic, Marija   +6 more
core  

Modulation of Epigenetic Control by Advanced Molecular Tweezers

open access: yesChemistry – A European Journal, EarlyView.
Tailored dimeric molecular tweezers recognize the DNA‐binding part of Histone H4 and interrupt the essential histone‐DNA interaction. ABSTRACT This work addresses the question if supramolecular systems can be tailored to interfere with posttranslational modifications (PTM) and epigenetics.
My‐Hue‐Le   +9 more
wiley   +1 more source

Maternal and Neonatal Complications Associated with Breast Cancer Systemic Treatments—A VigiBase Disproportionality Analysis Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pregnancy‐associated breast cancer (PrBC) presents therapeutic challenges. Understanding maternal–fetal safety of systemic anticancer therapies is critical. We performed a case/non‐case disproportionality analysis using the WHO global pharmacovigilance database up to January 2024, to evaluate maternal–fetal outcomes associated with breast cancer (BC ...
Rayan Kabirian   +12 more
wiley   +1 more source

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