Results 31 to 40 of about 262,172 (291)

Age features of the thymocite RNA response in the thymus structural and functional areas to blood circulation disorders in the pool of carotic arteries in rats

open access: yesJournal of Education, Health and Sport, 2023
Introduction. Ischemic-reperfusion injuries of the brain are accompanied by immunological disorders, which in their turn can extend post-ischemic changes in the brain.
S. Tkachuk   +4 more
doaj   +1 more source

THE THYMUS GLAND (THYMUS) ASPECTS IN CHILDREN (PART I)

open access: yesМать и дитя в Кузбассе, 2020
The thymus gland (thymus) is a huge mystery of biology, medicine (primarily immunology) and, in particular, pediatrics. Despite the fact that it has been calling attention of researchers for over 4 centuries.
Юрий Иванович Ровда   +3 more
doaj  

The role of the transcription factor Foxn1 in Thymus organogenesis and maintenance [PDF]

open access: yes, 2014
The thymus is the primary lymphoid organ responsible for T-cell development and selection, which requires a specialised stromal microenvironment. The thymic stroma consists mainly of thymic epithelial cells (TEC), which can be divided into cortical (c ...
Bosch, Angela Jeanne Tamara
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

The Thymus Gland (Thymus) Aspects in Children (Review of Literature)

open access: yes, 2022
The thymus gland (thymus) is a huge mystery of biology, medicine (primarily immunology) and, in particular, pediatrics. Despite the fact that it has been calling attention of researchers for over 4 centuries.
Azamovich, Nuraliev Akhror   +4 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Use of organ-culture, irradiation and adoptive-transfer to investigate the role of the xenopus thymus in t lymphocyte development [PDF]

open access: yes, 1986
This Thesis attempts to develop an amphibian model system for exploring the role of the thymus, particularly its stromal cells, in the acquisition of allotolerance. Inbred, clonal and cytogenetically- marked Xenopus are used in this work.
Russ, Jane Hannah
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

COMPARATIVE MORPHOLOGICAL STUDY OF QUANTITATIVE RATIOS OF LYMPHOCYTES AT DIFFERENT MATURITY STAGES IN THYMUS OF IMMATURE VERTEBRATES

open access: yesМедицинская иммунология, 2017
The main function of thymus, a central organ of lymphoid system, is to form a pool of immunocompetent autotolerant thymocytes. The process of lymphocyte differentiation within thymus largely depends on organization level of the vertebral animal and its ...
V. Ya. Yurchinsky, L. A. Moreva
doaj   +1 more source

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