Results 51 to 60 of about 34,213 (236)

Thyroglobulin as an evolving biomarker of iodine reserve in thyroid dysfunction assessment in pregnancy

Nigerian Journal of Medicine, 2022
Background: Despite the use of routine thyroid function tests, thyroid dysfunction is often missed in pregnant women, who may have fluctuating iodine reserves and this may be associated with an increased risk of adverse maternal and fetal outcomes due to
Terry Terfa Gbaa
doaj   +1 more source

Hypoxia Inhibitor Improves Iodine Uptake Disorder in Thyroid Cancer Through the hsa_circ_0023990/miR‐448/DNMT1/NIS Axis

Cancer Science, EarlyView.
Our study reveals that hypoxia inhibitors ameliorate iodine uptake dysfunction in thyroid cancer by acting on the hsa_circ_0023990/miR‐448/DNMT1/NIS signaling pathway. ABSTRACT This research seeks to investigate how hypoxia inhibitors enhance iodine uptake in thyroid cancer cells. Clinical samples were gathered and assessed for hsa_circ_0023990, DNMT1,
Ruiqin Gou, Shiqi Chen, Yangyang Lei, Pengqing Wu, Xuezhong Chen, Qing Zhang   +5 more
wiley   +1 more source

Postoperative Unstimulated Thyroglobulin Accurately Predicts Outcomes in High‐Risk Differentiated Thyroid Cancer: A Retrospective Cohort Study

Clinical Endocrinology, EarlyView.
ABSTRACT Objective High‐risk differentiated thyroid cancer (DTC) patients show variable outcomes. While postoperative stimulated thyroglobulin (STg) is a recognized predictive marker, the prognostic significance of unstimulated thyroglobulin (UTg) is still unexplored.
Julia Isabel Richter Cicogna, Sophia Yada Noguchi, Adriano Namo Cury, Giovanna Marcela Vieira Della Negra, Laís de Oliveira Teles Fraga, Marcelo Soares Schalch, Rafael de Cicco, Carolina Ferraz da Silva, Rosália Do Prado Padovani   +8 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

An Approach to the Structure of Thyroglobulin [PDF]

European Journal of Biochemistry, 1980
The mixture of CNBr peptides obtained by treatment of porcine thyroglobulin with cyanogen bromide was separated into three‐fractions by Sephadex G‐200 gel filtration in 1 M propionic acid. When one of these fractions was reduced and S‐alkylated, a hormone‐containing CNBr peptide was purified by filtration on Biogel A‐1.5 m and ion‐exchange ...
Christiane Arnaud, Claudine Marriq, Serge Lissitzky, Marcel Rolland   +3 more
openaire   +3 more sources

Ectopic thyroid carcinoma in the left atrium in a horse

Equine Veterinary Education, EarlyView.
Summary A 25‐year‐old Irish sport horse was presented for investigation of a 7‐day history of apathy and lethargy. Clinical examination revealed tachycardia, tachypnoea, distended, pulsating jugular veins and ventral oedema. Serum biochemistry showed azotaemia.
N. Wolf, J. Schläpfer, E. Dervas, S. Soto, I. L. Piotrowski   +4 more
wiley   +1 more source

Primary hyperparathyroidism in a domestic shorthair cat following I131 radioiodine therapy

Journal of Small Animal Practice, EarlyView.
A 12‐year‐old male neutered domestic shorthaired cat presented for further assessment of a cervical mass, having undergone radioiodine therapy for treatment of hyperthyroidism 2 years prior to presentation. Initial cytological diagnosis of the mass was supportive of a carcinoma and laboratory results were consistent with primary hyperparathyroidism ...
E. Ruane, P. Odatzoglou, H. Wong, A. Hayes   +3 more
wiley   +1 more source

The Highly Conserved Cys95 Residue of Fructose‐1,6‐Bisphosphatase 1 Mediates the pH‐Driven Structure and Activity of the Enzyme and Photosynthesis

Plant, Cell &Environment, EarlyView.
ABSTRACT In Arabidopsis, exposure to microbial volatile compounds promotes thiol reduction of the Cys95 residue of the photosynthetic enzyme fructose‐1,6‐bisphosphatase (cFBP1). Although highly conserved in plants, the Cys95 function still remains unknown. We characterised recombinant wild‐type (WT) cFBP1 and a variant (C95S) in which the Cys95 residue
Samuel Gámez‐Arcas, Edurne Baroja‐Fernández, Francisco José Muñoz, Antonio J. Serrato, Mónica Balsera, Ángela María Sánchez‐López, Abdellatif Bahaji, Jesús Leal‐López, Rafael Jorge León Morcillo, Javier Pozueta‐Romero   +9 more
wiley   +1 more source

Temporal Profiling of Male Cortical Astrocyte Transcription Predicts Molecular Shifts From Early Development to Aging

Glia, Volume 73, Issue 7, Page 1349-1364, July 2025.
Main Points Comprehensive analysis of cortical astrocyte gene expression across the lifespan. Profiling dynamic changes of key astrocyte genes reveals functional shifts. Astrocytes contribute to gene‐length‐dependent transcription decline in the aging brain.
Xiaoran Wei, Jiangtao Li, Michelle L. Olsen   +2 more
wiley   +1 more source

Ultrasound fundamentals and their clinical implications for interventional cytopathologists

Cytopathology, Volume 36, Issue 4, Page 356-374, July 2025.
Interventional cytopathologists need to know about ultrasound physics and instrumentation to produce an image that faithfully recreates the lesion discovered by the sonographer and diagnosed by the radiologist. A deep quantitative understanding of physics is not required.
David Lieu
wiley   +1 more source