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Association of serum thyroid-stimulating hormone and bone mineral density in Chinese adults with normal thyroid function. [PDF]
Nutr Metab (Lond)Chen J +10 more
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Inappropriate Secretion of Thyroid-Stimulating Hormone [PDF]
Annals of Internal Medicine, 1981 Recent studies have provided major new insights into the syndromes of inappropriate secretion of thyroid-stimulating hormone (TSH), a heterogeneous group of disorders in which patients show inappropriately elevated levels of serum immunoactive TSH in the presence of elevated free thyroid hormone levels.
Ione A. Kourides +3 more
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Physiological Reviews, 2002
This review focuses on recent advances in the structure-function relationships of thyroid-stimulating hormone (TSH) and its receptor. TSH is a member of the glycoprotein hormone family constituting a subset of the cystine-knot growth factor superfamily.
Bruce D. Weintraub +3 more
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This review focuses on recent advances in the structure-function relationships of thyroid-stimulating hormone (TSH) and its receptor. TSH is a member of the glycoprotein hormone family constituting a subset of the cystine-knot growth factor superfamily.
Bruce D. Weintraub +3 more
openaire +3 more sources
Endocrinology and Metabolism Clinics of North America, 2009
The thyroid-stimulating hormone receptor (TSHR) has a central role in thyrocyte function and is also one of the major autoantigens for the autoimmune thyroid diseases. We review the post-translational processing, multimerization, and intramolecular cleavage of TSHR, all of which may modulate its signal transduction.
Terry F. Davies +3 more
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The thyroid-stimulating hormone receptor (TSHR) has a central role in thyrocyte function and is also one of the major autoantigens for the autoimmune thyroid diseases. We review the post-translational processing, multimerization, and intramolecular cleavage of TSHR, all of which may modulate its signal transduction.
Terry F. Davies +3 more
openaire +2 more sources
Artifactual elevation of thyroid-stimulating hormone
The American Journal of Medicine, 1991A clinically euthyroid patient was found to have a normal serum thyroxine level and an elevated plasma thyrotropin (TSH) level measured by fluoroimmunoassay. Thyroid hormone therapy failed to suppress the TSH level. The TSH level was unresponsive to thyrotropin-releasing hormone (TRH) administration, alpha-subunits of pituitary glycoproteins were ...
Marion M. Brooks +3 more
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Journal of Endocrinology, 1984
ABSTRACT Previous studies have shown that freezing and thawing of human thyroid homogenates releases a water-soluble substance which reversibly binds to TSH-receptor antibodies. This substance has been designated long-acting thyroid stimulator absorbing activity (LAA).
B. Rees Smith, E. Davies Jones
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ABSTRACT Previous studies have shown that freezing and thawing of human thyroid homogenates releases a water-soluble substance which reversibly binds to TSH-receptor antibodies. This substance has been designated long-acting thyroid stimulator absorbing activity (LAA).
B. Rees Smith, E. Davies Jones
openaire +3 more sources
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2013
Background Macrocomplexes can be the cause of elevated serum hormone concentrations and may cause diagnostic confusion. This is well recognized for prolactin and commonly screened for using polyethylene glycol (PEG) precipitation. The phenomenon and a suitable screening method is less familiar with respect to thyroid-stimulating hormone (TSH).
Ruth M Ayling +4 more
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Background Macrocomplexes can be the cause of elevated serum hormone concentrations and may cause diagnostic confusion. This is well recognized for prolactin and commonly screened for using polyethylene glycol (PEG) precipitation. The phenomenon and a suitable screening method is less familiar with respect to thyroid-stimulating hormone (TSH).
Ruth M Ayling +4 more
openaire +3 more sources