Results 71 to 80 of about 454,057 (403)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Patterns of Thyroid Dysfunction among Women with Menstrual Disorder

Advanced Medical Journal
Background and objectives: Thyroid dysfunction can lead to menstrual irregularities and infertility. Thus, this study aimed to assess the frequency and patterns of thyroid dysfunction in patients with menstrual disorders.
Chrakhan Mohemmed Haji Rasul, Taha Othman Mahwy, Zagros Ghaffor Rashid   +2 more
doaj   +1 more source

Sick euthyroid syndrome: A myth or reality

Journal of Pediatric Critical Care, 2017
Altered thyroid function in non-thyroidal illness(NTI) is a well-recognized finding. The term euthyroid sick syndrome (SES) identifies abnormalities in thyroid function observed in patients with systemic nonthyroidal illnesses (NTIs).
Vinayak Patki, Aniket Kumbhojkar, Praveen Khilnani   +2 more
doaj   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Evaluation of thyroid function in a sample of newborns through different modes of delivery

Zanco Journal of Medical Sciences, 2019
Background and objective: Congenital hypothyroidism is the most common preventable cause of mental retardation detected during early childhood. Its early diagnosis is crucial for a better outcome.
Sasan L. Hanna, Awat I. Hamadamen, Dlair A.K. Chalabi   +2 more
doaj   +1 more source

Endocrinologic Control of Men's Sexual Desire and Arousal/Erection [PDF]

, 2016
Several hormones and neurotransmitters orchestrate men's sexual response, including the appetitive (sexual desire) and consummative (arousal and penile erection) phases.
Aversa, Antonio, Burnett, Arthur L., Corona, Giovanni, Isidori, Andrea, Maggi, Mario   +4 more
core   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Targeting the thyroid gland with thyroid-stimulating hormone (TSH)-nanoliposomes.

Biomaterials, 2014
Various tissue-specific antibodies have been attached to nanoparticles to obtain targeted delivery. In particular, nanodelivery systems with selectivity for breast, prostate and cancer tissue have been developed.
D. Paolino, D. Cosco, M. Gaspari, M. Celano, Joy Wolfram, Pasquale Voce, E. Puxeddu, S. Filetti, C. Celia, M. Ferrari, D. Russo, M. Fresta   +11 more
semanticscholar   +1 more source

Inappropriate secretion of thyroid-stimulating hormone [PDF]

Canadian Medical Association Journal, 2006
The Case: A 39-year-old man presented with fatigue and persistently elevated thyroid-stimulating hormone (TSH), free thyroxine (free T4) and free triiodothyrionine (free T3) levels. He was euthyroid by symptoms, and he did not report headaches or visual problems. He was not taking any medications,
Hasnain, Khandwala, Cheong, Lee
openaire   +2 more sources

Thyroxine-binding globulin: investigation of microheterogeneity [PDF]

, 1981
Preparations of T4-binding globulin (TBG) from human serum was performed using only two affinity chromatography steps. Purity of the protein was demonstrated by a single band in overloaded disc and sodium dodecyl sulfate electrophoresis, equimolar ...
Gärtner, Roland, Henze, R., Horn, K., Pickardt, C. R., Scriba, Peter Christian   +4 more
core   +1 more source