Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Background. A recent study has reported that high circulating 25-hydroxyvitamin D [25(OH)D] is associated with low circulating thyroid-stimulating hormone (TSH) levels, but only in younger individuals.
Qingqing Zhang +16 more
semanticscholar +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
The condition of endocrine system in young men athletes. [PDF]
Aim: to determine the functioning peculiarities of endocrine system of young men athletes. Material and methods. The were examined 84 athletes and 70 cadets of the Marine Academy. The check-up included the following procedures: the ultrasound examination
Megeryan C.D., Maslennikova О.М.
doaj
Suicide attempt of an overt hypothyroid patient with levothyroxine: A case report
Rationale: Levothyroxine is the most commonly used agent in thyroid hormone replacement therapy. Although there are many hypothyroid patients who use levothyroxine as a treatment, high level of thyroid stimulating hormone is found in a limited number of ...
Ayse Sahin Tutak
doaj +1 more source
HUBUNGAN KONTRASEPSI HORMONAL, POLA KONSUMSI IODIUM DAN GOITROGENIK DENGAN NILAI THYROID STIMULATING HORMONE STUDI PADA WANITA USIA SUBUR DI KLINIK BPP GAKI KABUPATEN MAGELANG TAHUN 2012 [PDF]
Masalah gizi di Indonesia salah satunya adalah Gangguan Akibat Kekurangan Iodium (GAKI). Pada saat ini, diperkirakan sebesar 12.989 orang Wanita Usia Subur di Jawa Tengah tinggal di 15 Kabupaten yang merupakan daerah kekurangan Iodium.
MIRDATILLAH, DWINA
core
Glycosylation in the thyroid gland : vital aspects of glycoprotein function in thyrocyte physiology and thyroid disorders [PDF]
The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins.
Ewa Pocheć +2 more
core +1 more source
Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan +19 more
wiley +1 more source
Thyroid stimulating hormone producing adenoma
DOI: 10.3969/j.issn.1672-6731.2015.08 ...
Xiao-ling YAN
doaj

