Results 151 to 160 of about 1,186,610 (361)

Case Studies in Thyroid and Parathyroid Tumors [PDF]

, 2023
Amit Agarwal, Ranil Fernando, Rajeev Parameswaran, Anand Mishra, Roma Pradhan   +4 more
openalex   +1 more source

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

Advanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, Thati Madhusudhan, Hongjie Wang, Xiong Zhong Ruan, Hesong Zeng   +13 more
wiley   +1 more source

Decoding the Tumor Microenvironment of Myoepithelial Cells in Triple-Negative Breast Cancer Through Single-Cell and Transcriptomic Sequencing and Establishing a Prognostic Model Based on Key Myoepithelial Cell Genes

International Journal of Genomics
Conclusion: This study highlights MECs’ role in TNBC progression, provides a CoxBoost prognostic model for personalized treatment, and identifies TPD52 as a potential therapeutic target for TNBC intervention.
Xiaocheng Yu, Ye Tian, Rui Zhang, Yong Yang   +3 more
doaj   +1 more source

Neovascular PSMA expression is a common feature in malignant neoplasms of the thyroid

, 2018
Birthe Heitkötter, Konrad Steinestel, Marcel Trautmann, Inga Grünewald, Peter Barth, Heidrun Gevensleben, Martin Bögemann, Eva Wardelmann, Wolfgang Hartmann, Kambiz Rahbar, Sebastian Huss   +10 more
openalex   +2 more sources

Induction of Specific Phosphodiesterase Isoforms by Constitutive Activation of the cAMP Pathway in Autonomous Thyroid Adenomas¹ [PDF]

, 2000
Luca Persani, Andrea Lania, Luisella Alberti, Roberto Romoli, Giovanna Mantovani, Sébastiano Filetti, Anna Spada, Marco Conti   +7 more
openalex   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

Advanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li, Tianqi Su, Bin Zhang, Wenkai Han, Sibin Zhang, Guiyin Sun, Yuwei Cong, Xin Chen, Jiping Qi, Yujie Wang, Shiguang Zhao, Hongxue Meng, Peng Liang, Xin Gao   +13 more
wiley   +1 more source

Long-term survival outcomes of neoadjuvant chemotherapy in stage II-III HR+/HER2- breast cancer

Scientific Reports
Breast cancer is the most common malignant tumor among women worldwide. Hormone receptor-positive/HER2-negative (HR+/HER2-) breast cancer is the largest subgroup among these cases.
Jiaxing Liu, Likuan Tan, Hongyu Zhang, Chengzhi Ma, Gang Qin, Shaolong Huang, Yang Long, Feng-hui He, Yao Huang, Miao-Miao Jiao, Yufei Liu, Guanghui Wang   +11 more
doaj   +1 more source

Selenoprotein Gene Expression in Thyroid and Pituitary of Young Pigs Is Not Affected by Dietary Selenium Deficiency or Excess

, 2009
Ji‐Chang Zhou, Hua Zhao, Jungang Li, Xinjie Xia, Kangning Wang, Yajun Zhang, Yan Liu, Ying Zhao, Xin Gen Lei   +8 more
openalex   +2 more sources

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Thyroid-Stimulating Hormone Favors Runx2-Mediated Matrix Mineralization in HOS and SaOS2 Cells: An In Vitro and In Silico Approach [PDF]

, 2022
Ramajayam Govindan, Mohamed El‐Sherbiny, Khalid Mohamed Morsy Ibraheem, S. Narasimhan, Mohamed EL-Dosoky Mohamed Salama, Fazil Ahmad, Selvaraj Jayaraman, Vishnu Priya Veeraraghavan, Srinivasan Vengadassalapathy, Krishna Mohan Surapaneni, Vidhya Rekha Umapathy, Gayathri Rengasamy, Shazia Fathima Jaffer Hussain, Maheshkumar Poomarimuthu, S Kalimuthu   +14 more
openalex   +1 more source