Results 151 to 160 of about 1,147,749 (362)

Early postoperative levothyroxine initiation after total thyroidectomy for Graves’ disease

open access: yesEndocrine Journal
No evidence-based standards exist regarding levothyroxine (LT4) replacement therapy initiation timing in patients with hyperthyroid Graves’ disease undergoing total thyroidectomy.
Yuji Nagayama   +11 more
doaj   +1 more source

Vitamin D Binding Protein, a Ligand of Integrin beta 1, Motivates Both Tumor Cells and Schwann Cells to Promote Perineural Invasion in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Group‐specific component protein (GC) promotes perineural invasion (PNI) in pancreatic ductal adenocarcinoma (PDAC) by activating Schwann cell dedifferentiation and by enhancing tumor–Schwann cell chemoattraction, independently of vitamin D transport. Integrin β1 (ITGB1) functions as a GC receptor in both cancer cells and Schwann cells.
Shan Zhang   +15 more
wiley   +1 more source

LncRNA CASC9 facilitates papillary thyroid cancer development and doxorubicin resistance via miR-28-3p/BCL-2 axis and PI3K/AKT signaling pathway

open access: yesJournal of Cardiothoracic Surgery
Background Papillary thyroid cancer (PTC) is a malignant tumor that poses a serious threat to human health. LncRNA CASC9 serves as an oncogene in numerous tumors.
Jianping Yu   +4 more
doaj   +1 more source

TSH Ligand‐Based CAR‐T Cell Effectively Eradicates TSHR‐Positive Thyroid Cancer with Favorable Safety Profile

open access: yesAdvanced Science, EarlyView.
TSHR is highly expressed in differentiated thyroid cancer (DTC), making it an ideal target for adoptive immune cell therapy. A novel Ligand‐based TSH‐CAR‐T cell approach effectively eradicated TSHR‐positive thyroid tumors in vitro and accomplished full remission in tumor models with favorable safety profile, highlighting that TSH‐CAR‐T cells could ...
Fei Wang   +10 more
wiley   +1 more source

ELECTRON MICROSCOPIC OBSERVATIONS ON THE THYROID [PDF]

open access: bronze, 1953
H Braunsteiner, K Fellinger, F. Pakesch
openalex   +1 more source

R‐APEX: A Knowledge Graph–Based Platform for the Elucidation of the Toxicological Mechanisms of Ambient Particulate Matter

open access: yesAdvanced Intelligent Systems, EarlyView.
R‐APEX is a knowledge graph platform developed to investigate how air pollutants such as particularly fine particulate matter (PM2.5) affect human health. By integrating large‐scale biomedical data and using machine learning, it reveals pollutant–gene–disease associations.
Zhixing Zhu   +7 more
wiley   +1 more source

Alterations in Signaling Pathways and Therapeutic Strategies of Traditional Chinese Medicine in Granulomatous Lobular Mastitis

open access: yesJournal of Inflammation Research
Mengdi Zhang,1 Dongqing Pu,2 Feifei Meng,1 Guangxi Shi,2 Jingwei Li2 1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan City, People’s Republic of China; 2Department of Thyroid and Breast Diagnosis and Treatment ...
Zhang M, Pu D, Meng F, Shi G, Li J
doaj  

Natural history and prognostic nomogram of untreated triple negative breast cancer based on SEER database

open access: yesScientific Reports
Triple-negative breast cancer (TNBC) is an aggressive subtype with a relatively poor prognosis, and its natural history without therapeutic intervention remains understudied.
Dasong Wang   +7 more
doaj   +1 more source

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