Results 161 to 170 of about 1,176,884 (363)

The Thyroid [PDF]

Postgraduate Medical Journal, 1957
openaire   +2 more sources

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

Advanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, Thati Madhusudhan, Hongjie Wang, Xiong Zhong Ruan, Hesong Zeng   +13 more
wiley   +1 more source

LncRNA CASC9 facilitates papillary thyroid cancer development and doxorubicin resistance via miR-28-3p/BCL-2 axis and PI3K/AKT signaling pathway

Journal of Cardiothoracic Surgery
Background Papillary thyroid cancer (PTC) is a malignant tumor that poses a serious threat to human health. LncRNA CASC9 serves as an oncogene in numerous tumors.
Jianping Yu, Chun He, Yun Peng, Yuzhong Wen, Jing Wang   +4 more
doaj   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Alterations in Signaling Pathways and Therapeutic Strategies of Traditional Chinese Medicine in Granulomatous Lobular Mastitis

Journal of Inflammation Research
Mengdi Zhang,1 Dongqing Pu,2 Feifei Meng,1 Guangxi Shi,2 Jingwei Li2 1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan City, People’s Republic of China; 2Department of Thyroid and Breast Diagnosis and Treatment ...
Zhang M, Pu D, Meng F, Shi G, Li J
doaj  

Hyperthyroidism in cats, part II : scintigraphic diagnosis and radioiodine treatment [PDF]

, 2016
In the second part of this review article, the diagnostic aspects of thyroid scintigraphy are discussed, with major emphasis on hyperthyroidism, followed by an overview of radioiodine ...
Daminet, Sylvie, Peremans, Kathelijne, Saunders, Jimmy, Vandermeulen, Eva, Volckaert, Veerle   +4 more
core   +1 more source

Network medicine approaches for identification of novel prognostic systems biomarkers and drug candidates for papillary thyroid carcinoma [PDF]

, 2023
Medi Kori, Kubra Temiz, Esra Göv
openalex   +1 more source

A Microfiber‐Reinforced Janus Hydrogel E‐Skin With Recyclable Feature for Multimodal Sensing and Gender‐Specific Physiological Monitoring

Advanced Science, EarlyView.
Hydrogel‐based wearable electronics hold great promise for physiological monitoring in privacy‐sensitive regions. In this study, a polyurethane (PU) microfiber‐reinforced gelatin hydrogel e‐skin is developed, boasting multiple advantages such as ultra‐thinness, high toughness, and long‐term skin conformability.
Yarong Ding, Yufeng Li, Shaozhe Tan, Jiachun Sun, Xu Yang, Xuesi Zhang, Zhenhua Lin, Zhenyu Li, Yue Hao, Yannan Liu, Yingchun Li, Jingjing Chang   +11 more
wiley   +1 more source

Natural history and prognostic nomogram of untreated triple negative breast cancer based on SEER database

Scientific Reports
Triple-negative breast cancer (TNBC) is an aggressive subtype with a relatively poor prognosis, and its natural history without therapeutic intervention remains understudied.
Dasong Wang, Yan Yang, Wei Rong, Li Fan, Lei Yang, Maoshan Chen, Hongwei Yang, Yu He   +7 more
doaj   +1 more source

Thyroid hormone preconditioning: Protection against ischemia-reperfusion liver injury in the rat

, 2006
Virginia Fernández, Iván Castillo, Gladys Tapia, Pamela Romanque, Sebastián Uribe-Echevarría, Mario Uribe, Denise Cartier-Ugarte, Gonzalo Santander, M Vial, Luis A. Videla   +9 more
openalex   +2 more sources