TERT Promoter Mutations in Papillary Thyroid Microcarcinomas [PDF]
, 2015 Small papillary thyroid carcinomas have contributed to the worldwide increased incidence of differentiated thyroid cancer observed over the past decades.
Bruno, Rocco +18 more
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External radiotherapy of thyroid cancer [PDF]
, 2001 Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
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Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation [PDF]
, 2013 Cancer arises through accumulation of epigenetic and genetic alteration. Aberrant promoter methylation is a common epigenetic mechanism of gene silencing in cancer cells.
Atsushi Kaneda +8 more
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A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid. Is conservative treatment always advised? [PDF]
, 2015 Introduction: Struma ovarii is an ovarian teratoma, represented in more than 50% by thyroid tissue. Five percent of struma ovarii cases have been proven to be malignant and, as in the thyroid gland, papillary thyroid carcinoma is the most common ...
Bianchi, Loredana +9 more
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Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma. [PDF]
, 2020 Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features
Mo, Joshua H +4 more
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Frequency and significance of Ras, Tert promoter, and Braf mutations in cytologically indeterminate thyroid nodules: A monocentric case series at a tertiary-level Endocrinology unit [PDF]
, 2017 PurposeThe management of thyroid nodules of indeterminate cytology is controversial. Our study aimed to establish the frequency and significance of H-,K-,N-RAS, TERT promoter, and BRAF gene mutations in thyroid nodes of indeterminate cytology and to ...
Barollo, Susi +13 more
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Recent advances in managing differentiated thyroid cancer [PDF]
, 2018 The main clinical challenge in the management of thyroid cancer is to avoid over-treatment and over-diagnosis in patients with lower-risk disease while promptly identifying those patients with more advanced or high-risk disease requiring aggressive ...
Durante, Cosimo +3 more
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A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer. Our experience in thyroid surgery [PDF]
, 2018 Background: Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA.
DE LUCA, Alessandro +6 more
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LGR5 is associated with tumor aggressiveness in papillary thyroid cancer. [PDF]
, 2015 PurposeLeucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a cancer stem cell marker and a down-stream target in Wnt/β-catenin signaling. In human papillary thyroid cancer (PTC), over activation of Wnt/β-catenin has been associated with
Diehl, Anna Mae +4 more
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Unmodifiable variables related to thyroid cancer incidence [PDF]
, 2018 The incidence of thyroid cancer is significantly different between male and female patients. Thyroid cancer is also the only form of cancer where age can be considered a staging variable.
Alecu, Lucian +10 more
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