Results 51 to 60 of about 94,067 (206)

Glycosylation in the thyroid gland : vital aspects of glycoprotein function in thyrocyte physiology and thyroid disorders [PDF]

, 2018
The key proteins responsible for hormone synthesis in the thyroid are glycosylated. Oligosaccharides strongly affect the function of glycosylated proteins.
Ewa Pocheć, Kamila Kozłowska, Marta Ząbczyńska   +2 more
core   +1 more source

Serum biomarkers of papillary thyroid cancer [PDF]

Journal of Otolaryngology - Head & Neck Surgery, 2013
Objective To identify serum biomarkers of papillary thyroid cancer. Methods Prospective analysis was performed of banked tumor and serum specimens from 99 patients with thyroid masses. Enzyme-linked immunosorbent assay (ELISA) was employed to measure levels of five serum proteins previously demonstrated to be up-regulated in papillary thyroid cancer ...
Makki, Fawaz M., Taylor, S. Mark, Shahnavaz, Ali, Leslie, Andrew, Gallant, Jeffrey, Douglas, Susan, Teh, Evelyn, Trites, Jonathan, Bullock, Martin, Inglis, Karen, Pinto, Devanand M., Hart, Robert D.   +11 more
openaire   +3 more sources

ACR‐TIRADS Institution and Effect on Thyroid Surgeries in Veterans: A 10‐Year Retrospective Study

The Laryngoscope, EarlyView.
Following analysis of the adoption of ACR TI‐RADS at the VA Northern California Healthcare System, the number of thyroid ultrasounds and FNAs increased substantially, while the total number of thyroid surgeries remained relatively stable. Surgical practice trends towards more selective and less‐invasive management, with fewer total thyroidectomies for ...
Isabella W. Leon, Davis S. Chong, Bryle Nicole G. Barrameda, Anusha A. Gogulapati, Lane D. Squires   +4 more
wiley   +1 more source

Synchronous primary papillary breast cancer, medullary thyroid carcinoma and neuroendocrine tumor in postmenopausal woman. [PDF]

, 2016
Multiple endocrine neoplasia are syndromes involving two or more endocrine tissues, often correlated to RET proto-oncogene mutations. We herein present the first reported case of a 57-years-old woman with three synchronous primary cancers of breast ...
DE IULIIS, Francesca, Lanza, Rosina, Lunardi, Gianluigi, Menghi, Antonello, Pecorella, Irene, Rossi, Lorena, Scarpa, Susanna, Sini, Valentina   +7 more
core  

Sarcoidosis mimicking metastatic papillary thyroid cancer

International Journal of Surgery Case Reports, 2015
Sarcoidosis is a multisystemic, idiopathic disease. It has a highly variable clinical course. It has been reported to present in association with malignancy. Coexistence of sarcoidosis and thyroid cancer is rarely reported in the literature.We present a case with neck swelling for 3 months, and symmetrical painless thyroid enlargement without fixation ...
Salih, Abdulwahid M., Fatih, Salah M., Kakamad, F.H.   +2 more
openaire   +2 more sources

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Whole‐Genome Bisulfite Sequencing Identifies Blood‐Based DNA Methylation Biomarker for Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Functional DNA methylation abnormalities are a hallmark of human cancers and may be a promising biomarker for their early diagnosis. Moreover, the largest methylation differences can improve the sensitivity of noninvasive diagnoses of solid tumors.
Junsheng Zhao, Sijia Shen, Junjie Zhang, Ying Xu, Jing Peng, Hainv Gao, Lanjuan Li   +6 more
wiley   +1 more source

Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]

, 2013
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher, Solomon, Daniel, Sosa, Julie Ann, Tuggle, Charles   +3 more
core   +1 more source

Molecular Diagnostics in Thyroid Nodules: Current Applications, Clinical Value, and Future Perspective

Med Research, EarlyView.
ABSTRACT Molecular diagnostics have become an important adjunct to ultrasonography and fine‐needle aspiration (FNA) for thyroid nodules, especially in Bethesda III/IV cytology where malignancy risk is uncertain. This narrative review summarizes the diagnostic and prognostic value of key genomic drivers (BRAF V600E, RAS, RET, TERT, and selected fusions)
Guohui Xiao, Min Ding, Zhixue Min, Yihan Dong, Xuanye Cao, Qiang Lu, Cong Chen, Yahui Wu, Xin Guo, Zhen Wu, Jing Xie, Dan Xu, Haizhen Chen, Rongli Xie, Jian Fei   +14 more
wiley   +1 more source

Mutational Analysis in Pediatric Thyroid Cancer and Correlations with Age, Ethnicity, and Clinical Presentation. [PDF]

, 2016
BackgroundWell-differentiated thyroid cancer (WDTC) incidence in pediatrics is rising, most being papillary thyroid carcinoma (PTC). The objective of the study was to assess the prevalence of different mutations in pediatric WDTC and correlate the ...
Cheng, Shih-Min, Hantash, Feras M, Jiang, Wen, McPhaul, Michael J, Newbury, Robert O, Newfield, Ron S, Nikita, Maria Eleni, Phillips, Susan A, Reitz, Richard E, Waldman, Frederic M   +9 more
core   +1 more source