Results 201 to 210 of about 447,839 (304)

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó, Natássia Elena Bufalo, Valdemar Máximo, Laura Sterian Ward   +3 more
wiley   +1 more source

The critical role of ferroptosis in thyroid cancer development and potential therapeutic implications. [PDF]

Front Oncol
Li Y, Qian T, Han Z, Wang C, Zhang M, Huang C, Gu Q, Zhang S, Lin Y, Wang J, Chen S.   +10 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

From DNA Methylation Microarray to Digital PCR: A Stepwise Strategy for Tissue Specific cfDNA Biomarker Development

Journal of Clinical Laboratory Analysis, EarlyView.
Overview of a DNA methylation biomarker development pipeline, from discovery and assay design to screening, performance evaluation, and specificity testing in clinical sample matrices. ABSTRACT Background Tissue‐specific cell‐free DNA (cfDNA) offers promise as a minimally invasive biomarker of organ injury.
David H. Murray, Nicky Boulter, Shanon Ranjit, Natasha M. Rogers, Sarah Kummerfeld, Jason P. Ross, Rodney J. Scott   +6 more
wiley   +1 more source

Special Issue "Molecular Biology of the Thyroid Cancer and Thyroid Dysfunctions". [PDF]

Int J Mol Sci
Vija L.
europepmc   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

MAPK13 promotes the progression of papillary thyroid cancer. [PDF]

Eur Thyroid J
Zhao R, Su Z, Wan Z, Qiao P, Lu Y, Chi Y, Zheng L, Zhang Y, Huang S, Chen X.   +9 more
europepmc   +1 more source

Deciphering nodal burden in thyroid carcinoma: A dedicated survey of age, lymph node ratio, log odds of positive nodes, and preoperative prediction models

Journal of Intelligent Medicine, EarlyView.
Abstract Evidence regarding the prognosis of thyroid carcinoma is heterogeneous, ranging from age effects and nodal burden metrics, such as lymph node ratio (LNR) and log odds of positive nodes (LODDS), to preoperative imaging models comprising ultrasound, CEUS, and radiomics.
Mennatallah Sherif, Mohanad A. Deif, Eman K. Elsayed   +2 more
wiley   +1 more source

Endocrine-disrupting chemicals and thyroid cancer. [PDF]

Turk J Med Sci
Baş Aksu Ö, Şahin M.
europepmc   +1 more source

Impact of Ceiling Suspended Shield Size on Primary Operator Radiation Dose During Coronary Angiography and Intervention

Journal of Medical Radiation Sciences, EarlyView.
Reducing radiation exposure to staff performing coronary angiography and intervention is an occupational health and safety priority for hospitals. We demonstrate that a larger lead acrylic shield, with lead rubber pleats on the lower edge will reduce radiation exposure to the cardiologist performing the procedure by approximately 40%. We recommend that
James A. Crowhurst, Elizabeth Andersen, Michael Savage, Jason Tse, Dale Murdoch, Darren Walters, Rustem Dautov   +6 more
wiley   +1 more source