Molecular Docking and Target‐Specific Binding Profiles of Benzosuberane‐Based Compounds
ChemMedChem, EarlyView.Benzosuberane represents a promising scaffold in medicinal chemistry. Several benzosuberane‐based derivatives are described in this review as anticancer agents, including antivascular agents, DNA‐intercalators, receptor modulators and kinase inhibitors.
Michail A. Saragatsis +3 more
wiley +1 more source
Comparison of irisin hormone expression between thyroid cancer tissues and oncocytic variant cells
Cancer Management and Research, 2019 Kader Ugur,1 Suleyman Aydin,2 Tuncay Kuloglu,3 Gokhan Artas,4 Mehmet Ali Kocdor,5 İbrahim Sahin,2,6 Meltem Yardim,2 İbrahim Hanefi Ozercan41Department of Endocrinology and Metabolism Disease, School of Medicine, Firat University, Elazig, Turkey ...
Ugur K +7 more
doaj
B7-H3 and ICAM-1 are potentially therapeutic targets for thyroid carcinoma
Diagnostic PathologyAlthough most differentiated thyroid carcinoma has a clinically favorable prognosis, some of specific types of thyroid cancer (such as anaplastic thyroid carcinoma and advanced papillary thyroid carcinoma) show fatal outcomes and require novel treatments.
Pengtao Song, Yongcan Xu, Guochao Ye
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Unusual Presentation of Cystic Papillary Thyroid Carcinoma
Case Reports in Endocrinology, 2012 Papillary thyroid carcinoma is the most common thyroid malignancy, accounting for 80% of all thyroid cancers. The most common presentation of thyroid cancer is an asymptomatic thyroid mass or a nodule.
Vijayraj S. Patil +2 more
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T cell receptor β‐chain repertoire analysis reveals the association between neoantigens and tumour‐infiltrating lymphocytes in multifocal papillary thyroid carcinoma [PDF]
, 2017 Zheming Lu +4 more
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Adult Ectopic Cervical Thymic Tissue in relation to a Parathyroid Adenoma and a Papillary Thyroid Carcinoma: A Report of Two Cases [PDF]
, 2020 Vijay Shrawan Nijhawan +3 more
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Predictive Factors for Skip Lymph Node Metastasis and Their Implication on Recurrence in Papillary Thyroid Carcinoma [PDF]
, 2022 Young Jae Ryu +4 more
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Clinical Pharmacology in Drug Development, EarlyView.Abstract ALG–055009 is an oral thyroid hormone receptor beta (THR‐β) agonist being evaluated for treating metabolic dysfunction–associated steatohepatitis (MASH). This study evaluated the safety, tolerability, pharmacokinetics, and pharmacodynamics of ALG‐055009 and bioavailability/food effect.
Hakim Charfi +11 more
wiley +1 more source
Minimally invasive video-assisted thyroidectomy for the early-stage differential thyroid carcinoma [PDF]
, 2012 Jianjun Yu +15 more
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Quantitative Approaches to Accelerate MASH Drug Discovery and Development
Clinical Pharmacology &Therapeutics, EarlyView.Metabolic dysfunction‐associated steatohepatitis (MASH) is a widespread liver condition that leads to cirrhosis, hepatic carcinoma, and increased mortality rates. In MASH, the diagnosis and accelerated approval of drugs are dependent on changes in histological endpoints; full approval requires lengthy outcomes trials.
Yasmeen Abouelhassan +6 more
wiley +1 more source