Results 141 to 150 of about 938,886 (254)

Tolerability of Adjuvant Nivolumab in Esophageal or Gastroesophageal Junction Cancer: A Real‐World Study

International Journal of Cancer, EarlyView.
ABSTRACT Adjuvant nivolumab is approved for esophageal or gastroesophageal junction cancer after neoadjuvant chemoradiotherapy and resection. In the CheckMate‐577 trial, Grade 3–5 nivolumab‐related adverse events (AEs) occurred in 5% of patients, with early discontinuation due to toxicity in 9%. However, real‐world data on immunotherapy‐related adverse
Michelle Koops van ’t Jagt, Anniek Strijdhorst, Tamara Jessica Huizer, Esther Albertien Kleibeuker, Sarah Derks, Bianca Mostert, Hanneke van Laarhoven, Jacco Juri de Haan   +7 more
wiley   +1 more source

Papillary thyroid carcinoma presenting as an asymptomatic pelvic bone metastases

, 2010
Thyroid carcinoma is rare comprising 1% of all malignancies and commonly presents as a neck lump. Papillary thyroid carcinoma unlike follicular thyroid carcinoma tends not to metastasise to distant sites.We present a case of papillary thyroid carcinoma ...
Siddiq S, Ahmad I, Colloby P
core  

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

How to manage medullary thyroid carcinoma: current treatment strategies. [PDF]

Drugs Context
Saltiki K, Karapanou O, Michalaki M, Effraimidis G.   +3 more
europepmc   +1 more source

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

International Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer, Scott J. Walker, Carsten O. Daub   +2 more
wiley   +1 more source

Concurrent Hashimoto Thyroiditis, Graves' Disease, and Papillary Thyroid Carcinoma: A Case Report. [PDF]

Reports (MDPI)
Berisha-Muharremi V, Humolli A, Telaku J, Kurshumliu F, Mati R.   +4 more
europepmc   +1 more source

Protein kinase inhibitors for treatment of thyroid carcinoma

, 2008
kinases involved in anaplastic thyroid carcinoma ...
SANTORO, MASSIMO
core  

Incidence and Predictors of Immune‐Related Hypothyroidism Under Pembrolizumab Across Gynecologic Malignancies and Melanoma: A Real‐World Cohort Study

International Journal of Cancer, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) frequently cause thyroid immune‐related adverse events (irAEs). Permanent hypothyroidism, the clinically most relevant phenotype, requires lifelong hormone replacement. We investigated its incidence, course, risk factors, and prognostic relevance under pembrolizumab.
Freya Koffka, Johann Kornowski, Elena Laakmann, Barbara Schmalfeldt, Tim Zell, Glenn Geidel, Christoffer Gebhardt, Pia Roser, Volkmar Müller, Julian Kött   +9 more
wiley   +1 more source

SUMOylation-Dependent Repression of BIRC7 by DNMT3a Suppresses Papillary Thyroid Carcinoma Progression. [PDF]

Cell Biochem Funct
Liu K, Su Z, Li H.
europepmc   +1 more source

Retrospective analysis of outcome after endometrial ablation with the NovaSure device: A German single‐center experience

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Evaluation of retrospective outcomes of NovaSure treatment in patients with abnormal uterine bleeding, including safety and cost‐effectiveness, and risk factors related to therapeutic outcomes. Subgroup analysis was conducted for patients who underwent concomitant surgical procedures, required subsequent interventions, and were ...
Oliver M. Schleicher, Felix Heindl, Julia Gocke, Katharina Keller, Lothar Häberle, Alaa Hamzeh, Christian Matek, Matthias W. Beckmann, Julius Emons   +8 more
wiley   +1 more source