The zebrafish model to identify new genes involved in thyroid development [PDF]
Thyroid organogenesis is a very complex developmental process that leads to the formation of an organ able to produce specific hormones through specification, migration, structural organization and functional differentiation of thyroid precursor cells ...
Porreca, Immacolata
core +1 more source
The article presents an experience of treatment of 67 patients with benign thyroid tumors with application of ethanol destruction using guidance of ultrasonic imaging.
V. A. Beloborodov +2 more
doaj +1 more source
QPRT: a potential marker for follicular thyroid carcinoma including minimal invasive variant : a gene expression, RNA and immunohistochemical study [PDF]
Background The differential diagnosis between follicular thyroid adenoma and minimal invasive follicular thyroid carcinoma is often difficult for several reasons.
Hansmann Martin-Leo +9 more
core +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Progressive evolution of thyroid adenoma to thyroid carcinoma
Nodules (adenomas), enlarged thyroid (goiter) and inflammation of the thyroid (thyroiditis) are the most important risk factors for thyroid cancer. Adenomas have the largest increase in risk.
Aisyah Elliyanti
doaj +1 more source
Pathogenesis Markers of Hashimoto's Disease—A Mini Review
Hashimoto’s thyroiditis (HT) is the most common autoimmune disease involving the thyroid gland. HT often clinically manifest as hypothyroidism due to the destruction of thyroid cells mediated by humoral and cellular immunity.
Binghui Jin, Shuang Wang, Zhe Fan
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Role of Twist1 transcription factor in thyroid tumor progression [PDF]
Thyroid carcinomas are the most common endocrine tumors in humans, with a globally increasing incidence. Differentiated tumors, such as papillary (PTC) and follicular (FTC) thyroid cancers, are often curable with surgical resection and radiotherapy ...
Bencivenga, Tammaro Claudio
core +1 more source
Diagnosis of bone metastasis from thyroid carcinoma: a multidisciplinary approach
Sarcomas are rare tumors originating from soft tissue or bone. Diagnosis and treatment of sarcomas should be performed at specialized sarcoma centers, where patients are evaluated at a multidisciplinary tumor conference.
Thor Bechsgaard +3 more
doaj +1 more source
IL-34 Expression Is Reduced in Hashimoto's Thyroiditis and Associated With Thyrocyte Apoptosis
Hashimoto's thyroiditis (HT) is a common autoimmune disease accompanied by lymphocyte infiltration and thyroid tissue destruction. IL-34 was first described in 2008, and its involvement in the development of many autoimmune diseases has been recently ...
Shuo Wang +7 more
doaj +1 more source

