Results 61 to 70 of about 25,812,240 (142)

Transcriptomic and Metabolomic Analyses in Monozygotic and Dizygotic Twins

American Journal of Medical Genetics Part A, Volume 197, Issue 4, April 2025.
ABSTRACT Monozygotic (MZ) and dizygotic (DZ) twins are studied to understand genetic and environmental influences on complex traits, however the mechanisms behind twinning are not completely understood. (Epi)genomic studies identified SNPs associated with DZ twinning and DNA methylation sites with MZ twinning.
Nikki Hubers, Gabin Drouard, Rick Jansen, René Pool, Jouke Jan Hottenga, Miina Ollikainen, Xiaoling Wang, Gonneke Willemsen, Jaakko Kaprio, Dorret I. Boomsma, Jenny van Dongen   +10 more
wiley   +1 more source

Reduced sensitivity to thyroid hormones is associated with lung function in euthyroid individuals

Heliyon
Background: The thyroid gland exhibits a subtle interconnection with the lungs. We further investigated the correlation between thyroid hormone sensitivity and lung function in euthyroid individuals.
Zhaoxiang Wang, Bing Lu, Menghuan Wu, Tian Gu, Mengjiao Xu, Fengyan Tang, Li Zhang, Song Bai, Shao Zhong, Qichao Yang   +9 more
doaj   +1 more source

Melanin and Neurotransmitter Signalling Genes Are Differentially Co‐Expressed in Growing Feathers of White and Rufous Barn Owls

Pigment Cell &Melanoma Research, Volume 38, Issue 2, March 2025.
The colouration of the ventral face of barn owls varies from white to rufous, depending on the MC1R (V126I) genotype. This colouration is linked to multiple fitness and behavioural traits. Genes linked to neurotransmitters and synapses are upregulated with melanin genes in a transcriptome of growing feathers from the ventral part of chicks of the ...
Anne‐Lyse Ducrest, Luis M. San‐Jose, Samuel Neuenschwander, Emanuel Schmid‐Siegert, Céline Simon, Marco Pagni, Christian Iseli, Hannes Richter, Nicolas Guex, Tristan Cumer, Emmanuel Beaudoing, Mélanie Dupasquier, Pauline Charruau, Pauline Ducouret, Ioannis Xenarios, Jérôme Goudet, Alexandre Roulin   +16 more
wiley   +1 more source

Impaired central sensitivity to thyroid hormone is associated with hypertriglyceridemia in euthyroid population

Frontiers in Endocrinology
BackgroundWe aimed to investigate the correlation between central thyroid hormone sensitivity and Hypertriglyceridemia (HTG) in euthyroid population.MethodsA total of 833 individuals who underwent physical examinations were randomly selected. Biochemical
Yu Gong, Yu Gong, Guojuan Wang, Qianqian Zhang, Xu Jiang, Zhangxiang Zhu, Ying Li   +6 more
doaj   +1 more source

Effects of thyroid-stimulating hormone and sensitivity to thyroid hormones on the risk of hyperuricemia in euthyroid adults [PDF]

Archives of Endocrinology and Metabolism
Objective: The current study was conducted to investigate whether thyroid-stimulating hormone (TSH) and thyroid hormone sensitivity are associated with hyperuricemia probability in euthyroid population.
Hongzhan Ding, Yanyu Liang, Yilin Wang, Kexin Zhang, Mengya Zhu, Yang Jing, Yong Xue, Xiaofang Chen, Hui Zhou, Chen Dong   +9 more
doaj   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +2 more sources

Reduced central thyroid hormone sensitivity is associated with adverse body composition and lower biological age acceleration in euthyroid adults

European Journal of Medical Research
Background Central thyroid hormone sensitivity reflects the responsiveness of the hypothalamic-pituitary-thyroid feedback axis to circulating thyroid hormones.
Xin Zhao, Minne Sun, Yunlu Sheng, Jing Yu, Xiaona Li, Qun Zhang, Jianming Wang, Guoxian Ding   +7 more
doaj   +1 more source

Association between central thyroid hormone dysregulation and chronic kidney disease in type 2 diabetes: a cross-sectional study

Renal Failure
This cross-sectional study investigated the association between central thyroid hormone resistance and chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM) who have normal peripheral thyroid hormones.
Heming Huang, Yanjia Shi, Ping Fang, Sijing Tang, Wei Xu, Chenxia Zhou, Yun Zhou, Keqin Zhang, Ying Xue   +8 more
doaj   +1 more source

The circadian rhythm: A key variable in aging?

Aging Cell, Volume 23, Issue 11, November 2024.
In this study, general age‐related transcriptional trajectories in seven organs were investigated over the lifespan of mice. Since both sexes and two strains were used equally, biases in this regard are diminished. Twenty replicas per time provide a deeper insight than usual.
Patrick R. Winterhalter, Adrian‐Iustin Georgevici, Nitin J. Gharpure, Gábor Szabó, Andreas Simm   +4 more
wiley   +1 more source

Conditional quantile processes based on series or many regressors [PDF]

Quantile regression (QR) is a principal regression method for analyzing the impact of covariates on outcomes. The impact is described by the conditional quantile function and its functionals. In this paper we develop the nonparametric QR series framework,
Victor Chernozhukov, Alexandre Belloni, Ivan Fernandez-Val   +2 more
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