Cognitive functions and thyroid hormones secretion disorders
, 2021 Mateusz Przybylak +2 more
openalex +1 more source
Relationship between caffeine intake and thyroid function: results from NHANES 2007–2012 [PDF]
, 2023 Jiaping Zheng +7 more
openalex +1 more source
Early detection of biochemically occult autonomous thyroid nodules [PDF]
, 2016 Objective: Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism, but may exist even in the presence of normal TSH.
Brusca, Nunzia +7 more
core +1 more source
Advanced Science, EarlyView.This study unveils ITGA2⁺ tumor cells as key drivers of pediatric thyroid cancer aggressiveness. These cells orchestrate dual oncogenic pathways: GLUT1‐mediated glycolytic reprogramming and M2 macrophage polarization. This metabolic‐immunological crosstalk promotes tumor progression and metastasis.
Zhi‐jun Zhan +11 more
wiley +1 more source
Predicting risk of malignancy in patients with indeterminate thyroid nodules [PDF]
, 2018 Thyroid cancer is the most prevalent endocrine cancer (1). The prevalence of palpable thyroid nodules in the general adult population is 4% to 7% (2). Ultrasound imaging detects thyroid nodules in 19%-68% of randomly selected individuals (3). The rate of
Carnes, Nicholas
core
Triiodothyronine and free thyroxine levels are differentially associated with metabolic profile and adiposity-related cardiovascular risk markers in euthyroid middle-aged subjects [PDF]
, 2014 Background: We previously showed that in healthy young men a less favorable body composition is associated with higher FT3 levels within the euthyroid range.
De Buyzere, Marc +6 more
core +2 more sources
TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition
Advanced Science, EarlyView.This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang +16 more
wiley +1 more source
Thyroid Function in Newly Diagnosed HIV-positive Patients
, 2023 Soutrik Kumar Dutta +1 more
openalex +1 more source
Subclinical thyroid dysfunction and cardiovascular diseases: 2016 update. [PDF]
, 2017 Subclinical thyroid dysfunction comprises subclinical hypothyroidism (SHypo), defined as elevated thyroid-stimulating hormone (TSH) by normal free thyroxine (FT4), and subclinical hyperthyroidism (SHyper) with decreased or undetectable TSH and normal FT4.
Collet, T.H. +3 more
core +3 more sources
Disruption of NF‐κB‐Mediated Copper Homeostasis Sensitizes Breast Cancer to Cuproptosis
Advanced Science, EarlyView.This study reveals a feedback mechanism regulating copper homeostasis, in which copper directly interacts with TAK1 to activate NF‐κB signaling, while NF‐κB transcriptionally suppresses copper transporter (CTR1) expression. These findings highlight a promising therapeutic strategy for breast cancer by combining NF‐κB inhibitors with copper chelators or
Xiaomei Zhang +16 more
wiley +1 more source