Results 91 to 100 of about 467,067 (355)

Diagnostic Dilemma In Discordant Thyroid Function Tests Due To Thyroid Hormone Autoantibodies

AACE Clinical Case Reports, 2017
: Objective: Assay interference could be the cause of abnormal thyroid function tests. Early recognition prevents inappropriate patient management. The objective of this report is to present a case with discordant thyroid function tests in different ...
Panudda Srichomkwun, MD, Neal H. Scherberg, PhD, Jasminka Jakšić, MD, Samuel Refetoff, MD   +3 more
doaj  

The role of primary cilia in thyroid diseases

Frontiers in Endocrinology
Primary cilia (PC) are non-motile and microtube-based organelles protruding from the surface of almost all thyroid follicle cells. They maintain homeostasis in thyrocytes and loss of PC can result in diverse thyroid diseases. The dysfunction of structure
Zijiao Tian, Xinlin Li, Xue Yu, Shuxin Yan, Jingwei Sun, Wenxin Ma, Xiaoyun Zhu, Yang Tang   +7 more
doaj   +1 more source

Effect of Antiepileptic Drug Treatment on Thyroid Hormone Levels in Epilepsy Patients

Haseki Tıp Bülteni, 2019
Aim:Antiepileptic drugs (AEDs) can have an effect on hormone metabolism and function, and alter serum levels of some hormones. This study aimed to determine the effects of AEDs on thyroid function test results in epilepsy patients.Methods:The study ...
Aytül Mutlu
doaj   +1 more source

Diagnostic Use of Radionuclides in Diseases of the Thyroid [PDF]

, 1975
Since the introduction of radionuclides into clinical medicine, a number of specific tests have been designed to test thyroid function and to diagnose disease of the thyroid gland.
Sharpe, Alton R., Jr.
core   +1 more source

S-nitrosylation of NF-kB p65 inhibits TSH-induced Na+/I- symporter expression [PDF]

, 2015
Nitric oxide (NO) is a ubiquitous signaling molecule involved in a wide variety of cellular physiological processes. In thyroid cells, NO-synthase III-endogenously produced NO reduces thyrotropin (TSH)-stimulated thyroid specific gene expression ...
Bocco, Jose Luis, Lucero, Ariel Maximiliano, Masini, Ana María, Montesinos, Maria del Mar, Nazar, Magalí, Nicola, Juan Pablo, Pellizas, Claudia Gabriela, Peyret, Victoria, Romero, Jorge Miguel   +8 more
core   +3 more sources

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

Advanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang, Ye Zhang, Zhu Liu, Zhiyuan Wang, Huaqin Wang, Xiaoyu Ji, Hongyue Su, Fan Yang, Lirong Yan, Ying Xu, Hao Zhang, Wei Sun   +11 more
wiley   +1 more source

Gait patterns associated with thyroid function: The Rotterdam Study [PDF]

, 2016
Gait is an important health indicator and poor gait is strongly associated with disability and risk of falls. Thyroid dysfunction is suggested as a potential determinant of gait deterioration, but this has not been explored in a population-based study ...
Bano, A. (Arjola), Chaker, L. (Layal), Darweesh, S.K.L. (Sirwan), Dehghan, A. (Abbas), Franco, O.H. (Oscar), Geest, J.N. (Jos) van der, Ikram, M.K. (Kamran), Korevaar, T.I.M. (Tim), Mattace Raso, F.U.S. (Francesco), Peeters, R.P. (Robin)   +9 more
core   +1 more source

The Non‐Canonical ChREBPα Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF‐β‐E2F1 Axis

Advanced Science, EarlyView.
Intrahepatic microenvironment greatly impacts duration and degree of HSCs activation and development of liver fibrosis. By inhibiting TGFβ‐E2F1‐driven production of profibrogenic factors (CTGF and THBS1), hepatocyte ChREBPα monitors hepatic microenvironment and suppresses the overactivation of HSCs.
Jian Zhang, Yuee Zhao, Gauthami Pulivendala, Qing Zhang, Liangyou Rui, Jiashi Gao, Huiwen Wang, Gary Zhang, Alli Nuotio‐Antar, Xin Tong, Lei Yin   +10 more
wiley   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source