Results 141 to 150 of about 510,329 (306)

Reduced sensitivity to thyroid hormones is associated with lung function in euthyroid individuals

open access: yesHeliyon
Background: The thyroid gland exhibits a subtle interconnection with the lungs. We further investigated the correlation between thyroid hormone sensitivity and lung function in euthyroid individuals.
Zhaoxiang Wang   +9 more
doaj   +1 more source

Association Between Thyroid Function and Oxidative Stress Markers in Overt and Subclinical Hypothyroid Patients: Observational Cross-Sectional Study in Nepal [PDF]

open access: hybrid
Fuleshwar Mandal   +7 more
openalex   +1 more source

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang   +18 more
wiley   +1 more source

Relationship between dietary selenium intake and serum thyroid function measures in U.S. adults: Data from NHANES 2007–2012 [PDF]

open access: gold, 2022
Fang Liu   +8 more
openalex   +1 more source

Thyroid function tests in endemic goitre [PDF]

open access: yes, 1967
Alberts, H.   +4 more
core   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang   +12 more
wiley   +1 more source

Effectiveness of Bariatric Surgery for Improving Thyroid Function and Reducing Levothyroxine Dose in Patients With Obesity and Overt Hypothyroidism [PDF]

open access: diamond, 2023
Hanan H Alfaifi   +5 more
openalex   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

open access: yesAdvanced Science, EarlyView.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua   +31 more
wiley   +1 more source

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