Results 141 to 150 of about 517,911 (354)

AI‐Guided SERS Defines a Pan‐Cancer Diagnostic Biomarker

Advanced Science, EarlyView.
An AI‐enabled SERS platform integrates automated exosome enrichment with molecular fingerprinting to enable accurate early detection and differential diagnosis of ten common cancers. The system identifies exosomal dATP as a universal Raman biomarker, offering a scalable, noninvasive, and clinically translatable approach for precision oncology ...
Cai Zhang, Wen‐Hui Zhao, Duo Zuo, Tianxing Zhou, Wenjing Hou, Lingwei Wang, Shangheng Shi, Yang Yang, Yuanyuan Liu, Shao‐Kai Sun, Li Ren, Zhaoxiang Ye, Dingbin Liu, Dong Li, Xiaoyuan Chen, Jihui Hao   +15 more
wiley   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

Advanced Science, EarlyView.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang, Shucheng Jin, Penghui Guo, Yuying Yin, Yichun Hua, Xiaosheng Ding, Zhe Zhang, Shuo Chen, Xu Han, Baowang Li, Yan Liu, Xiaoyan Li, Deling Li, Jing Jing, Wei Shi, Wang Jia   +15 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Polychlorinated naphthalenes in the serum of individuals with thyroid dysfunction and their potential mechanisms of impact on disease progression

Emerging Contaminants
Polychlorinated naphthalenes (PCNs) comprise 75 congeners, with varying concentrations and major congeners across different populations. Recent studies have found a relationship between PCNs and thyroid hormone levels, suggesting they may interfere with ...
Yuhao Fan, Dan Chen, Xinyu Lou, Ye Wu, Jie Sun, Zhiyan Liu, Jun Jin, Tan Chen   +7 more
doaj   +1 more source

Lithium in Drinking Water and Thyroid Function

, 2011
Karin Bröberg, Gabriela Concha, Karin Engström, Magnus Lindvall, Margareta Grandér, Marie Vahter   +5 more
openalex   +1 more source

Carotid Beta Stiffness Association with Thyroid Function [PDF]

, 2021
Alessandro Delitala, Angelo Scuteri, Edoardo Fiorillo, Valeria Orrù, Edward G. Lakatta, David Schlessinger, Francesco Cucca   +6 more
openalex   +1 more source

Metal–Organic Framework Featuring Monodispersed Silver Cation Sites for Highly Efficient and Selective Extraction of Aqueous Iodide Anions

Advanced Science, EarlyView.
A novel cationic metal–organic framework (MOF‐monoAg) featuring monodispersed silver (Ag+) sites is developed for the highly selective extraction of aqueous iodide ions (I−). MOF‐monoAg exhibits high accessibility, selectivity, and binding affinity toward I− ions, enabling superior iodine extraction from seawater and efficient iodide removal from ...
Xuewen Cao, Jiacheng Zhang, Jinjiao Pan, Yan Li, Yue Ma, Xinfeng Du, Lijuan Feng, Boyang Huang, Yihui Yuan, Liang Mao, Ning Wang, Abdullah M. Al‐Enizi, Ayman Nafady, Shengqian Ma   +13 more
wiley   +1 more source

RNA Sequencing Identifies Multiple Fusion Transcripts, Differentially Expressed Genes, and Reduced Expression of Immune Function Genes in BRAF (V600E) Mutant vs BRAF Wild-Type Papillary Thyroid Carcinoma [PDF]

, 2013
Robert C. Smallridge, Ana-Maria Chindris, Yan W. Asmann, John D. Casler, Daniel Serie, Honey V. Reddi, Kendall W Cradic, Michael Rivera, Stefan K. Grebe, Brian M. Necela, Norman L. Eberhardt, Jennifer M. Carr, Bryan McIver, John A. Copland, E. Aubrey Thompson   +14 more
openalex   +1 more source

Effects of Tobacco Exposure on Maternal Thyroid Function During the First Trimester of Pregnancy [PDF]

, 2022
Rabia Zehra Bakar, Çağlar Çetin, Can Yılmaz Yozgat, Mehmet Serdar Kütük   +3 more
openalex   +1 more source

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

Advanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, Thati Madhusudhan, Hongjie Wang, Xiong Zhong Ruan, Hesong Zeng   +13 more
wiley   +1 more source