Results 121 to 130 of about 5,895,005 (299)

Autoimmune thyroid disease with fluctuating thyroid function. [PDF]

PLoS Medicine, 2005
Ali S Alzahrani, Saleh Aldasouqi, Suzan Abdel Salam, Ali Sultan   +3 more
doaj   +1 more source

The effect of ambient temperature on thyroid function parameters: a daily level panel study

BMC Public Health
Background The association between season and thyroid function parameters has been extensively studied, but the non-linear and lagged effects of extremely low ambient temperature on thyroid function parameters remain unknown.
Tao Wang, Hailin Ma, Zhaoqing Jin, Ting Yang, Zhiqiang Zhao, Aerdake Wulalibieke, Qishan Wang, Yu Cao, Shenghong Yang   +8 more
doaj   +1 more source

Thyroid function and atrial fibrillation: Is there a mediating role for epicardial adipose tissue?

, 2018
Daniel Bos,1–3,* Arjola Bano,2,4,5,* Albert Hofman,1,2 Tyler J VanderWeele,1 Maryam Kavousi,2 Oscar H Franco,2 Meike W Vernooij,2,3 Robin P Peeters,2,4,5 M Arfan Ikram,1,2 Layal Chaker,1,2,4,5 1Department of Epidemiology, Harvard T.H.
Vernooij MW, Kavousi M, Franco OH, Hofman A, Chaker L, Ikram MA, Bano A, Bos D, Peeters RP, VanderWeele TJ   +9 more
core  

Thyrostimulin (a TSH-like Hormone) Expression in Orbital and Thyroid Tissue

, 2007
Objective: To investigate gene expression of thyrostimulin in orbital and thyroid tissue from patients with and without Graves' disease. Design: Real-time reverse transcriptase polymerase chain reaction (RT-PCR) was used for detection of thyrostimulin ...
Capretz, Annika, Nilsson, Emma, Åsman, Peter,, Hallengren, Bengt,, Frenander, Christofer,, Bondeson, Anne-Greth,, Planck, Tereza,, Ridderstråle, Martin,, Lantz, Mikael,, Lund University., Groop, Leif,, Åberg, Magnus,   +11 more
core   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Therapeutic strategies to target the receptor tyrosine kinase AXL in thyroid cancer

, 2012
The AXL receptor tyrosine kinase is overexpressed and active in various cancer types including thyroid carcinoma, and several preclinical studies suggest that targeting AXL is an effective therapeutical strategy in AXL-positive cancers.
MELILLO, ROSA MARINA, GnanaPrakasam Krisnamoorthy, VISCIANO, CARLA, CARLOMAGNO, Francesca, LIOTTI, FEDERICA, GUIDA, TERESA   +5 more
core  

ERα–PADI4–CXCL8 Axis Drives MDSC‐Mediated Immune Evasion in Anaplastic Thyroid Carcinoma

Advanced Science, EarlyView.
MAPK‐driven ligand‐independent ERα activation drives PADI4 transcription and translation. This enzyme then modifies CXCL8 chemokines through citrullination, generating a potent chemoattractant gradient specifically for myeloid‐derived suppressor cells.
Dongdong Zhang, Ying Cai, Junbin Zhang, Jianyong Zhang, Ran Jing, Ming Cai   +5 more
wiley   +1 more source

Association between thyroid function and thyroid homeostasis parameters and the prevalence and all-cause and cardiovascular mortality of chronic kidney disease: a population-based study

BMC Public Health
Background To evaluate the relationship between thyroid function and thyroid homeostasis parameters with the prevalence of chronic kidney disease (CKD) and furtherly explore the all-cause and cardiovascular mortality among individuals with CKD using data
Xue Liu, Yuhao Zhang, Yuchen Li, Xiude Fan, Haiqing Zhang   +4 more
doaj   +1 more source

Pathogenesis of endocrine thyroid cancer [PDF]

, 2015
This review aims to discuss the different genetic alterations that may come about and thus give rise to thyroid cancer. The importance of understanding the pathogenesis of this disease is in the use of these genetic alterations as prognostic markers and ...
Vassallo, Josanne, Mallia, Nicola
core  

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source