Results 151 to 160 of about 11,357,056 (401)

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

AMIODARONE THERAPY AIDED CHANGES IN THE THYROID GLAND FUNCTIONS AMONG THE CHILDREN

Педиатрическая фармакология, 2006
The results of research of thyroid condition and function in 82 children with dilated cardiomyopthy and arrhythmogenic dysfunction of myocardium without obvious thyropathy are submitted.
N.R. Belova, E.N. Arsen'eva, I.E. Sulaberidze, E.N. Basargina, G.M. Dvoriakovskaya, V.V. Botvin'eva, N.V. Malakhova   +6 more
doaj   +2 more sources

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Salicylates and Thyroid Function. I. Depression of Thyroid Function [PDF]

Journal of Clinical Investigation, 1958
F K, AUSTEN, M E, RUBINI, W H, MERONEY, J, WOLFF   +3 more
openaire   +2 more sources

In Vivo Anabolic Androgenic Steroid Alters Thyroid Gland Functions in Female Rats

, 2022
Ali Abdulhussein, Shihab Hattab Mutlag, Mahmood Kahtan, Elaf Dawood, Nasrollah Shahidi, Andrew Parkinson, Nick Evans, Rodrigo Fortunato, A Fragkaki, Michael Bahrke, Charles Yesalis, Shehzad Basaria, Justin Wahlstrom, Adrian Dobs, A Meikle, B Dirlikov, S Lavoie, K Shem, M Alen, P Rahkila, M Reinil, R Vihko, Asma Aljaberi, Hessa Md, Boharoon, Md   +25 more
openalex   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Image-guided thermal ablation in autonomously functioning thyroid nodules. A retrospective multicenter three-year follow-up study from the Italian Minimally Invasive Treatment of the Thyroid (MITT) Group

, 2021
Giovanni Mauri, Enrico Papini, Stella Bernardi, Daniele Barbaro, Roberto Cesareo, Pierpaolo De Feo, Maurilio Deandrea, Laura Fugazzola, Giovanni Gambelunghe, Gabriele Greco, Carmelo Messina, Salvatore Monti, Alberto Mormile, Roberto Negro, Chiara Offi, Andrea Palermo, Luca Persani, Federica Presciuttini, Luigi Solbiati, Stefano Spiezia, Fulvio Stacul, Marco Viganò, Luca Maria Sconfienza   +22 more
openalex   +2 more sources

609P The association between thyroid function abnormalities and vitiligo induced by pembrolizumab regarding prognosis in patients with advanced melanoma [PDF]

, 2023
Moez Jawad Mobarek, Ahmed Zuhair Alsammarraie, R. Mohammed Hussein, Hadi Skouri   +3 more
openalex   +1 more source

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

Thyroid function and postmenopause

Gynecological Endocrinology, 2003
There is an increasing prevalence of high levels of thyroid stimulating hormone (TSH) with age - particularly in postmenopausal women - which are higher than in men. The incidence of thyroid disease in a population of postmenopausal women is as follows: clinical thyroid disease, about 2.4%; subclinical thyroid disease, about 23.2%. Among the group with
openaire   +2 more sources