Results 91 to 100 of about 8,604,077 (300)

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Diagnosis of thyroid disease: Principles and problems [PDF]

Journal of Medical Biochemistry, 2010
Conceptually, thyroid disorders can be classified into four groups, namely: 1. disorders of thyroid morphology, 2. disorders of thyroid function, 3. presence of thyroid autoimmunity, and 4. diagnosis and follow-up of thyroid carcinoma.
Žarković Miloš
doaj  

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

PSYNDEX Tests Review für TRR 1 - TESTS ZU RECHNEN UND RAUMLEHRE 1

, 1984
This is a PSYNDEX Tests Review of TRR 1 - TESTS ZU RECHNEN UND RAUMLEHRE 1. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Proekel, Gerhard
core   +1 more source

Congenital Hypothyroidism; is There any Familial Component?

مجله دانشکده پزشکی اصفهان, 2009
Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study
Nasibeh Hasani, Bahar Dehghan, Masood Amini, Kamal Heidari, Ali Sajadi, Ali Ajami, Masoomeh Dastanpour, Rezvaneh Hadian, Ashraf Aminoroaya, Zahra Pournaghshband, Silva Hovsepian, Mahin Hashemipour   +11 more
doaj  

Urinary phthalate and thyroid function tests in Hashimoto’s thyroiditis

The Egyptian Journal of Internal Medicine
Background Although Hashimoto’s thyroiditis was recognized over a century ago, its precise cause is still unclear. There are raised concerns that plasticizers like phthalate are related to exacerbation of HT.
Salah Hussien Elhalwany, Yara Mohamed Ahmed Eid, Laila Mahmoud Hendawy, Hoda Adel Afifi, Mohanad Osman Norain Ahmed, Caroline Adel Girgis Bishay   +5 more
doaj   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

PSYNDEX Tests Review für RCT (3) - READING COMPREHENSION TESTS 3

, 1984
This is a PSYNDEX Tests Review of RCT (3) - READING COMPREHENSION TESTS 3. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Proekel, Gerhard
core   +1 more source

SOX30 Facilitates Triple‐Negative Breast Cancer Metastasis via TNFR2–NF‐κB Signaling and Tumor Microenvironment Remodeling

Advanced Science, EarlyView.
SOX30 drives triple‐negative breast cancer (TNBC) metastasis through a dual mechanism: direct activation of the TNFR2/NF‐κB signaling cascade and subsequent CCL20‐mediated recruitment of tumor‐associated macrophages (TAMs) into the tumor microenvironment.
Pingping Gao, Na Sun, Ning Yang, Tingting Zhao, Rui Fu, Zhenyu Wu, Yuqin Zhou, Xuanni Tan, Yi Zhang, Fei Han, Xiaowei Qi   +10 more
wiley   +1 more source

Relation between Thyroid Function Tests and Body Mass Index among Thyroid Dysfunction Patients

UHD Journal of Science and Technology
Background: Obesity has the potential to impact thyroid function through various pathways, even in individuals considered euthyroid. The relationship between thyroid function and body mass index (BMI) remains a subject of ongoing debate.
Sanaa Othman Karim, Kalthum Mohammed Gharib, Maisam Hama Murad Majeed, Hadeel Abdulelah Ibrahim, Bayan Omar Sharif, Diman F. Salih, Balen F. Hamasaeed   +6 more
doaj   +1 more source