Results 101 to 110 of about 240,133 (294)

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Early prediction of transient versus permanent congenital hypothyroidism: a retrospective cohort study [PDF]

Annals of Pediatric Endocrinology & Metabolism
Purpose Early differentiation between transient congenital hypothyroidism (TCH) and permanent congenital hypothyroidism (PCH) is crucial for optimizing the duration of treatment.
Myung Ji Yoo, Ji-Eun Lee, Eun Young Joo, Jisun Park, Young Ju Suh, Su Jin Kim   +5 more
doaj   +1 more source

Thyrotoxicosis and coexistent diseases in atrial fibrillation [PDF]

, 2008
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenObjective: To evaluate the prevalence of thyrotoxicosis and coexistent diseases in patients with atrial fibrillation admitted to a general medicine ward ...
Ari Jóhannesson, Birgir Jóhannsson, Sigurður Ólafsson, Uggi Agnarsson   +3 more
core  

Electrochemically Engineered PEDOT:PSS/MXene Composite Electrode for the Label‐Free Procalcitonin Detection

Advanced Materials Interfaces, EarlyView.
Procalcitonin is a key biomarker for bacterial infections, but conventional detection methods are often time‐consuming. Here, we present an electrochemical sensor based on highly conductive Ti3C2Tx MXene combined with PEDOT:PSS, enabling direct antibody immobilization, while a bovine serum albumin coating provides antifouling protection.
Angelika Banaś, Roman Turczyn, Maciej Krzywiecki, Izabela Matuła, Sara Shakibania, Katarzyna Krukiewicz, Deivasigamani Ranjith Kumar   +6 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Congenital Hypothyroidism; is There any Familial Component?

مجله دانشکده پزشکی اصفهان, 2009
Background: Congenital hypothyroidism (CH) is a relatively common congenital disorder in neonates. Recently, a considerable proportion of familial cases have been identified, and possible roles of autoimmune factors suggested. The aim of this study
Nasibeh Hasani, Bahar Dehghan, Masood Amini, Kamal Heidari, Ali Sajadi, Ali Ajami, Masoomeh Dastanpour, Rezvaneh Hadian, Ashraf Aminoroaya, Zahra Pournaghshband, Silva Hovsepian, Mahin Hashemipour   +11 more
doaj  

Diagnosis of thyroid disease: Principles and problems [PDF]

Journal of Medical Biochemistry, 2010
Conceptually, thyroid disorders can be classified into four groups, namely: 1. disorders of thyroid morphology, 2. disorders of thyroid function, 3. presence of thyroid autoimmunity, and 4. diagnosis and follow-up of thyroid carcinoma.
Žarković Miloš
doaj  

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Thyroid Hormones and Interference in Thyroid Function Tests: A Review

Journal of Applied Sciences and Environmental Management
The objective of this paper was to provide a critical and concise review on thyroid hormones and what constitutes interference in thyroid function tests using appropriate Online resources.Thethyroid function tests, play a valuable and significant role ...
O. O. Edet, E. A. Omon, M. C. Agwu, A. N. Eze, M. E. Nwigube   +4 more
doaj  

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source