Results 121 to 130 of about 8,604,077 (300)

ZMIZ2–DUX4–LGR5 Signaling Axis Maintains Stemness Properties and Facilitates Docetaxel Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study identifies ZMIZ2 as a therapeutic target for docetaxel‐resistant triple‐negative breast cancer, sustaining cancer stemness‐associated properties and docetaxel resistance. ZMIZ2 upregulation enhances DUX4‐mediated LGR5 activation through the SWI/SNF components BRG1 and BAF57.
Xueting Gan, Shulei Sun, Ran Hu, Yuheng Feng, Xinhao Wu, Fangqi Liu, Xuyong Lin, Xiupeng Zhang, Xuezhu Rong, Qiang Han   +9 more
wiley   +1 more source

Distinct PXR Inverse Agonism Mechanisms Rely on Differential Ligand‐induced Co‐Regulator Recruitment

Angewandte Chemie, EarlyView.
Pregnane X receptor (PXR) antagonism is ligand‐encoded: SPA70 recruits corepressors NCoR1 (nuclear receptor corepressor 1)/SMRT (silencing mediator for retinoid and thyroid‐hormone receptors) while binding coactivators, and is modulated by retinoid X receptor alpha (RXRα); MI891 causes cytoplasmic retention and corepressor‐dependent repression ...
Rajamanikkam Kamaraj, Azam Rashidian, Dharani Sai Sreekanth Nellore, Levi Miederer, Ivana Mejdr, Radim Nencka, Thales Kronenberger, Petr Pavek   +7 more
wiley   +2 more sources

Correlation between native CT density of thyroid parenchyma and thyroid function tests

Research in Diagnostic and Interventional Imaging, 2022
Dr. Padma Vikram Badhe, M.D., Dr. Moinuddin Sultan, M.D., Dr. Sanika Patil, DMRD, Dr. Ajith Varrior, Dr. Tejas Ghodasara, Dr. Gautham Shankar, Dr. Satyam Barchha   +6 more
doaj   +1 more source

PSYNDEX Tests Review für MDT 8 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 8. SCHULSTUFE

, 1983
This is a PSYNDEX Tests Review of MDT 8 - MATHEMATIK-DIDAKTISCHE TESTS FÜR DIE 8. SCHULSTUFE. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Lukesch, Helmut
core   +1 more source

Sacral Neural Crest‐Derived Extracellular Vesicles Promote Pelvic Ganglion Repair Through Anti‐Pyroptotic Effects Involving ANXA1–FPR2 Signaling

Advanced Science, EarlyView.
Extracellular vesicles derived from human pluripotent stem cell‐derived sacral neural crest cells promote repair of injured major pelvic ganglia and improve colorectal function. These vesicles reduce oxidative stress and pyroptosis, with ANXA1–FPR2 signaling contributing to their protective effects, and show a favorable therapeutic profile compared ...
Ting Yang, Wenwei Liu, Hufei Wang, Yuxin Wu, Yuanchen Ma, Xiaofeng Wang, Tianxiang Lei, Qiao Tang, Yebohao Zhou, Weiqiang Li, Andy Peng Xiang, Wu Song   +11 more
wiley   +1 more source

Thyroid testing in primary hypothyroidism

African Journal of Primary Health Care & Family Medicine
Thyroid hormones regulate essential metabolic processes and development. The hypothalamic–pituitary–thyroid axis regulates hormone production, with thyroid-stimulating hormone (TSH) levels being a key indicator of thyroid function in primary ...
Anshula Ambasta, Guillaume Grenet, Jessica Otte, Wade Thompson, Kenneth Bassett, Thomas Perry   +5 more
doaj   +1 more source

PSYNDEX Tests Review für LKT 5-6 - Lesekompetenz-Tests

, 2006
This is a PSYNDEX Tests Review of LKT 5-6 - Lesekompetenz-Tests. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Mayer, Anne-Kathrin
core   +1 more source

Comparative Evaluation of Chelator‐Conjugated Peptides for Lead‐Labeled SSTR2‐Targeted Theranostics: Integrated Computational Modeling and Preclinical Validation

Advanced Science, EarlyView.
The study integrates density functional theory with radiochemical and biological validation to compare DOTA‐, PSC‐, and DOTAM‐based chelator‐conjugates for 203Pb/212Pb theranostic applications. Distinct differences in metal coordination, electrostatic properties, conformational flexibility, cellular uptake, biodistribution, and dosimetry are identified
Jeongyun Kim, Na Yeon Han, Ayman Muzammal, Jae Hun Ahn, Changkeun Im, Sujin Kim, Sairan Eom, Choong Mo Kang, Ku Kang, Yong Jin Lee, Kyo Chul Lee, Michael K. Schultz, Dongyoul Lee   +12 more
wiley   +1 more source

Reference Intervals and Cut-Off Values for Thyroid Tests in the Croatian Adult Population on the Snibe MAGLUMI X6 Immunoassay Analyzer

Diagnostics
Background/Objectives: To establish reference intervals (RIs) and cut-off values for thyroid-related tests on the MAGLUMI X6 immunoassay analyzer (Snibe Diagnostic, Shenzhen, China) in an adult Croatian population.
Ivana Lapić, Dragana Šegulja, Željkica Jakoplić, Iva Lukić, Dunja Rogić   +4 more
doaj   +1 more source

THYROID FUNCTION TESTS [PDF]

Journal of Clinical Pathology, 1969
openaire   +2 more sources